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ELLIPTECINE
SynDRA canonical compound SYN0001145 — structure-anchored drug synonym record
| Primary target(s) | TOP2B |
|---|
| Mechanism of action | Topoisomerase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CYP1A1
- PIM1
- PIM2
- CLK3
- CLK1
- KIT
- CDK2
- PLK1
- PDPK1
- PIM3
- PMP22
- PLK4
- PAK6
- POLB
- POLH
- POLI
- POLK
- PBK
- ALDH1A1
- PRKAA2
- PAK4
- OXSR1
- NR3C1
- NPSR1
- NPC1
- NFKB1
- NFE2L2
- NEK6
- NEK2
- MTOR
- MPHOSPH8
- MBNL1
- MAPT
- MAPK6
- PAK5
- PRKACA
- MAPK11
- PTBP1
- VRK2
- VRK1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- A4
- MITF
- INS
- JAK2
- KAPCA
- KPCD1
- LYAG
- M3K3
- M3K5
- M4K2
- MCL1
- MDM2
- MDM4
- MDR1
- MLP3A
- ABC3F
- NCF1
- NCOA1
- NLRP1
- NNMT
- NPR1
- NPR2
- PNMT
- PPARG
- PPP1CA
- ROCK2
- STK33
- TLR3
- IL1B
- IFNG
- IFNB1
- IDHC
- ABC3G
- AHR
- APAF
- ATRX
- B2CL1
- CAC1H
- CDC25B
- CFTR
Drug classes
- Antineoplastic Agents
- Uncoupling Agents
Cross-references
Synonyms
- Ellipticine
- Elliptisine
- 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole
- NSC-71795
- TCMDC-125546
- 5,11-Dimethyl-6H-pyrido(4,3-b)carbazole
- ICIG 770
- 5,11-Dimethylpyrido[4,3-b]carbazole
- CCRIS 2003
- CP 5
- UNII-117VLW7484
- NSC71795
- EINECS 208-264-0
- CHEMBL123
- BRN 0221300
- MLS000736786
- MLS000028487
- CHEBI:4776
- 6H-Pyrido(4,3-b)carbazole, 5,11-dimethyl-
- CCG-36483
- 117VLW7484
- SMR000058370
- 6H-Pyrido[4,3-b]carbazole,5,11-dimethyl-
- 6H-Pyrido[4,3-b]carbazole, 5,11-dimethyl-
- SR-01000003083
- Ellipticin
- ellipticine
- RefChem:136522
- DTXCID90122346
- MFCD00010524
- Ellipticine?
- 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole; CP 5; NSC 71795
- ellipticine, HCl
- 5,3-b]carbazole
- Prestwick_194
- Ellipticine, synthetic
- ELLIPTICINE [MI]
- Opera_ID_1748
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