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LOXOPROFEN
SynDRA canonical compound SYN0001142 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | cyclooxygenase inhibitor | prostanoid receptor antagonist |
|---|
| Indication | pain relief |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- PTGS2 INHIBITOR
- Cyclooxygenase inhibitor
- PTGS1 INHIBITOR
- prostanoid receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- OPRK1
- ACHE
- HTR6
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KMT2A
- KCNH2
- HTT
- HTR3A
- MLNR
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GHSR
- FYN
- MC5R
- MMP1
- ESR2
- MMP9
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SIGMAR1
- PTPRC
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
- M02A · TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
Cross-references
Synonyms
- loxoprofen sodium hydrate
- loxonin
- loxoprofen sodium
- sodium loxoprofen
- Loxoprofene
- Loxoprofeno
- Loxoprofen acid
- Loxoprofen gel
- Loxonin
- Loxonin Pap
- Loxonin Tape
- CS-600G
- LX-A
- LX-P
- Loxonin Gel 1%
- Lipoxin A, Daiichi Sankyo/Lead Chemical
- Lipoxin A, Sankyo/ Lead Chemical
- Loxoprofen (gel, pain/ inflammation), Daiichi Sankyo
- Loxoprofen (gel, pain/ inflammation), Sankyo
- Loxoprofen (patch, pain/inflammation), Daiichi Sankyo/ Lead Chemical
- Loxoprofen (patch, pain/inflammation), Sankyo/ Lead Chemical
- 2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid
- Loxoprofenum
- 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid
- 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoic acid
- DTXCID9025164
- CHEBI:76172
- CS 600
- 2-(4-((2-oxocyclopentyl)methyl)phenyl)propionic acid
- 2-OCPPP
- 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic Acid
- RefChem:924941
- Koloxo
- Loxoprofen [INN]
- MFCD00864331
- Loxoprofen sodium hydrate
- Loxoprofen (INN)
- NCGC00015594-02
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