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MISOPROSTOL
SynDRA canonical compound SYN0001127 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGER1 | PTGER2 | PTGER3 | PTGER4 | PTGIR |
|---|
| Mechanism of action | prostanoid receptor agonist |
|---|
| Indication | duodenal ulcer disease |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- PTGER3
- PTGER2
- PTGER4
- PTGIR
- PTGER1
- PTGFR
Mechanisms of action (all sources)
- PTGER3 AGONIST
- Prostanoid EP3 receptor agonist
- prostanoid receptor agonist
- PTGIR ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NPY1R
- ADORA1
- OPRD1
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- LMNA
- MAOA
- MAPT
- MC3R
- MLNR
- NPSR1
- NR1I2
- NR3C1
- OPRK1
- HTR1A
- OPRM1
- PDE3A
- PDE4D
- PGR
- POLB
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- TDP1
- HTR2A
- HRH3
- ADORA2A
- CCKAR
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP2D6
- CP3A7
- NPY2R
- PE2R2
- PE2R4
Drug classes
- Prostaglandin E1 Analog
- Abortifacient Agents
- Abortifacient Agents, Nonsteroidal
- Anti-Ulcer Agents
- Gastrointestinal Agents
- Oxytocics
- Reproductive Control Agents
ATC classes
- G02A · UTEROTONICS
- A02B · DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
- ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- ARTHROTEC
- Arthrotec
- CYTOTEC
- Cytotec
- DICLOFENAC SODIUM AND MISOPROSTOL
- cytotec
- isprelor
- misoprost
- misoprostil
- SC-29333
- Misoprostol component of arthrotec
- Mysodelle
- Topogyne
- GyMiso
- Isprelor
- Misopess
- Misoprostolum
- Misotol
- Cytotec (TN)
- Misoprostolum [INN-Latin]
- XP-16J
- Misoprostol (JAN/USAN/INN)
- SC 29333
- misoprostol (usp-rs)
- ARTHROTEC COMPONENT MISOPROSTOL
- 0E43V0BB57
- misoprostol (usp monograph)
- misoprostol (ep monograph)
- DTXCID70897
- Apo Misoprostol
- misoprostolo
- Novo Misoprostol
- Misoprostol 1%
- RefChem:55654
- Misoprostol 1% Dispersion
- CHEBI:63610
- A02BB01
Reported adverse events
- Bleeding
- GI bleed
- Perforation
- Ulceration
- Abortion
- Uterine rupture
- P
- Elderly
- Abdominal pain
- Hypersensitivity
- Dyspepsia
- Flatulence
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