← SynDRA
IMETIT
SynDRA canonical compound SYN0001126 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HRH3 | HRH4 |
|---|
| Mechanism of action | histamine receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- HRH3 FULL AGONIST
- HRH4 FULL AGONIST
- histamine receptor agonist
- HRH3 AGONIST
- HRH4 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2A
- ADGRF1
- NFE2L2
- HTR1B
- HTR1E
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- HTR5A
- HTR6
- HTR7
- KAT2A
- MAPT
- MBD4
- NEIL1
- NPSR1
- HDAC6
- OGG1
- OPRD1
- OPRK1
- OPRM1
- S1PR1
- SIGMAR1
- SLC6A2
- SLC6A3
- SMUG1
- TDG
- TDP1
- THPO
- TMEM97
- HRH1
- GPR35
- ADRA1A
- CHRM3
- ADRA1B
- ADRA1D
- ADRA2B
- ADRA2C
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- COMT
- CP2D6
- CP3A4
- GAMT
- GNMT
- HNMT
- NNMT
- PNMT
- TPO
Drug classes
Cross-references
Synonyms
- S-(2-(4-Imidazolyl)ethyl)isothiourea
- UNII-677MJ4VPZC
- 2-(1H-Imidazol-4-yl)ethyl carbamimidothioate
- 677MJ4VPZC
- CHEMBL19439
- CHEBI:64156
- 2-(1h-imidazol-5-yl)ethyl carbamimidothioate
- Carbamimidothioic acid, 2-(1H-imidazol-4-yl)ethyl ester
- 2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
- C6H10N4S
- Carbamimidothioic acid,2-(1H-imidazol-5-yl)ethyl ester
- S-[2-(4-imidazolyl)ethyl]isothiourea
- Tocris-0729
- Lopac-I-135
- AC1Q7DRW
- ACMC-20m57g
- AC1L1GI2
- Lopac0_000645
- SCHEMBL114670
- GTPL1250
- DTXSID8043737
- 2-(1H-Imidazol-5-yl)ethyl carbamimidothioate
- 2-(1H-imidazol-5-yl)ethyl imidothiocarbamate
- RefChem:909061
- DTXCID6023737
- {[2-(1H-imidazol-5-yl)ethyl]sulfanyl}methanimidamide
- Imetit (dihydrobromide)
- 2-(1~{H}-imidazol-5-yl)ethyl carbamimidothioate
- VUF 8325 (dihydrobromide);SKF 91105 (dihydrobromide)
- ITF
- {[2-(1H-imidazol-4-yl)ethyl]sulfanyl}methanimidamide
- SCHEMBL2895693
- Carbamimidothioic acid, 2-(1H-imidazol-5-yl)ethyl ester
- BDBM22911
- BDBM50405121
- BDBM50483134
- MFCD14636193
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