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MOXONIDINE
SynDRA canonical compound SYN0001093 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | NISCH |
|---|
| Mechanism of action | Imidazoline receptor agonist |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- NISCH
- ADRA2A
- ADRA2C
- ADRA2B
- Adra2b
- HTR1A
- Htr1a
- Nisch
Mechanisms of action (all sources)
- Imidazoline receptor agonist
- NISCH AGONIST
- Nischarin agonist
- ADRA2A AGONIST
- ADRA2B AGONIST
- ADRA2C AGONIST
- ADRA2A INHIBITOR
- ADRA2C INHIBITOR
- ADRA2B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- ACHE
- LCK
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- KCNH2
- NR1I2
- IDH1
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HSPA5
- HRH3
- HRH2
- HRH1
- HMGCR
- NPY2R
- NR3C1
- GMNN
- PTPRC
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antihypertensive Agents
- Cardiovascular Agents
ATC classes
- C02A · ANTIADRENERGIC AGENTS, CENTRALLY ACTING
- ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION
Cross-references
Synonyms
- normoxocin
- moxonidin
- Moxonidina
- BDF-5896
- BDF5896
- BE-5895
- BE5895
- LY-326869
- LY326869
- Cynt
- Fisiotens
- Normatens
- Physiotens
- BDF-5895
- Normoxin
- AC1OCENE
- SCHEMBL1230620
- Moxonidine hydrochloride hydrate
- moxonidine hydrochloride monohydrate
- 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine hydrate hydrochloride
- Norcynt
- Nucynt
- Moxonidinum
- CC6X0L40GW
- BE 5895
- LY 326869
- DTXCID3025170
- RefChem:819554
- C02AC05
- BDF5895
- Lomox
- MFCD00865794
- NCGC00015649-02
- Normoxocin
- CAS-75438-57-2
- Moxonidinum [Latin]
- Moxonidina [Spanish]
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