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PIRENPERONE
SynDRA canonical compound SYN0001074 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HTR2A |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Serotonin receptor antagonist
- HTR7 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- HTR2C
- ARSA
- MAPT
- THPO
- TDP1
- SMN1
- SLCO1B3
- SLCO1B1
- SAMHD1
- PMP22
- PKM
- MBNL1
- KCNH2
- KDM4E
- ATAD5
- HPGD
- HDAC6
- ERG
- EHMT2
- DRD1
- CYP3A4
- CYP2D6
- CBX1
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- 5HT7R
- ACES
- CP2D6
- CP3A7
- DRD2
- DRD3
- ESR1
- ESRRA
- GPR151
- S1PR4
Drug classes
Cross-references
Synonyms
- Pirenperona
- NSC-760095
- R-47,465
- R-47465
- 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
- R 47465
- NSC 760095
- CHEMBL18331
- 3-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- MLS000069365
- Y9FMC4513X
- 4H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-2-methyl-
- NCGC00015784-07
- SMR000058507
- Pirenperona [INN-Spanish]
- Pirenperonum
- Pirenperonum [INN-Latin]
- CAS- 75444-65-4
- SR-01000002998
- EINECS 278-213-5
- UNII-Y9FMC4513X
- Pirenperone [USAN:INN:BAN]
- 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- 3-(2-(4-(4-FLUOROBENZOYL)PIPERIDIN-1-YL)ETHYL)-2-METHYL-4H-PYRIDO(1,2-A)PYRIMIDIN-4-ONE
- Prestwick_858
- Spectrum_001584
- SpecPlus_000663
- Lopac-P-126
- Opera_ID_1876
- Prestwick0_000531
- Prestwick1_000531
- Prestwick2_000531
- Prestwick3_000531
- Spectrum2_001680
- Spectrum3_001655
- Spectrum4_000620
- Spectrum5_001827
- PIRENPERONE [INN]
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