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CYSTEAMINE
SynDRA canonical compound SYN0001066 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | NPY2R | SST | TGM2 |
|---|
| Mechanism of action | tissue transglutaminase inhibitor |
|---|
| Indication | cystinosis |
|---|
| Disease area | metabolism |
|---|
All known targets
Mechanisms of action (all sources)
- tissue transglutaminase inhibitor
- SST BINDER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALDH1A1
- HDAC6
- USP1
- TSHR
- TDP1
- SLC22A1
- RGS4
- POLI
- PLK1
- NFE2L2
- MAPT
- LMNA
- GMNN
- ALDH2
- EHMT2
- EHMT1
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- CFTR
- CBX1
- BLM
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CASP1
- DRD3
- NLRP1
- NTM1A
- NTMT1
- PRMT1
Drug classes
- Cystine Disulfide Reduction
- Cystine Depleting Agents
- Cystine Depleting Agent
ATC classes
- A16A · OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
- S01X · OTHER OPHTHALMOLOGICALS
Cross-references
Synonyms
- CYSTADROPS
- CYSTAGON
- CYSTARAN
- Cystadrops
- Cystagon
- Cystaran
- PROCYSBI
- Procysbi
- mercaptamine
- mercaptamine hydrochloride
- mercaptamine bitartrate
- thioethanolamine
- 2-mercaptoethylamine
- mercamine
- mercaptamin
- mercaptoethylamine
- cysteamine bitartrate
- procysbi
- cystagon
- cysteamine hydrochloride
- cysteamine HCl
- Mercaptamine
- Mercaptamina
- L-1573
- MEA
- NSC-647528
- Becaptan
- Cisteamina
- Cystavision
- Cysteamide
- Cysteamin
- Cysteinamine
- Decarboxycysteine
- Ethanethiolamine
- Lambraten
- Lambratene
- Mecramine
- Mercamin
Reported adverse events
- Vomiting
- Abdominal pain
- Headache
- Lethargy
- Leukopenia
- Nervousness
- Somnolence
- Joint hyperextension
- Hypertension
- Nausea
- Dehydration
- Dizziness
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