← SynDRA
PLERIXAFOR
SynDRA canonical compound SYN0001048 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CXCR4 |
|---|
| Mechanism of action | CCK receptor antagonist |
|---|
| Indication | multiple myeloma | non-Hodgkin lymphoma (NHL) |
|---|
| Disease area | hematologic malignancy |
|---|
All known targets
- CXCR4
- ACKR3
- CCR4
- CCR2
- CXCL12
- Cxcr4
Mechanisms of action (all sources)
- CCK receptor antagonist
- CXCR4 PARTIAL AGONIST
- C-X-C chemokine receptor type 4 partial agonist
- ACKR3 AGONIST
- CXCR4 ANTAGONIST
- CC chemokine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CHRM1
- HRH3
- ADRA2C
- SLC6A3
- CHRM2
- HTR3A
- OGG1
- NTHL1
- MAOA
- KDR
- KCNH2
- KAT2A
- HTR2A
- HTR2B
- HTR1E
- HTR1D
- HTR1B
- HTR1A
- HRH4
- OPRD1
- ACHE
- HRH1
- SLC6A2
- TMEM97
- TDP1
- TDG
- TBXA2R
- SMUG1
- SLC6A4
- SIGMAR1
- OPRK1
- S1PR1
- PTGS1
- PGR
- PDE4A
- PDE3A
- OPRM1
- HRH2
- GPR35
- HDAC6
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Hematopoietic Stem Cell Mobilizer
ATC classes
Cross-references
Synonyms
- MOZOBIL
- Mozobil
- plerixafor hydrochloride
- plerixafor HCl
- AMD3100
- AMD 3100
- mozobil
- PLERIXAFOR OCTAHYDROCHLORIDE
- Plerixafor hydrochloride
- JM 3100
- SID 791
- Plerixafor accord
- AMD-3100
- JM 2987
- JM-3100
- JM3100
- SDZ SID 791
- SID791
- Bicyclam JM-2987
- Mozobil (TN)
- GNA & AMD-3100
- HHA & AMD-3100
- Plerixafor (INN/USAN)
- S915P5499N
- SDZ-SID-791
- plerixaforum
- JKL 169
- CHEBI:125354
- mezobil
- RPA bicyclam
- RefChem:57592
- DTXCID60817494
- L03AX16
- bicyclam JM-2987
- MFCD05662218
- Plerixafor 8HCl
- C28H54N8
Look up PLERIXAFOR in the interactive SynDRA portal →