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CHRYSIN
SynDRA canonical compound SYN0000968 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | ABCG2 | AKR1B1 | CDK6 | CYP19A1 | CYP1B1 |
|---|
| Mechanism of action | breast cancer resistance protein inhibitor |
|---|
All known targets
- CYP1B1
- AKR1B1
- CDK6
- CYP19A1
- ABCG2
- CYP1A1
- Malaria fabG
Mechanisms of action (all sources)
- CYP1A1 INHIBITOR
- CYP1B1 INHIBITOR
- breast cancer resistance protein inhibitor
- AKR1B1 INHIBITOR
- CYP19A1 INHIBITOR
- Malaria fabG INHIBITOR
- CDK6 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB1
- CA4
- TYR
- PSMB5
- PPARG
- NR3C1
- HDAC6
- FTO
- CYP2C9
- CYP1A2
- CBR1
- CA9
- CA7
- XDH
- CA2
- CA12
- AR
- AKR1B10
- CA1
- PDK1
- PIM1
- POLH
- PPARA
- PPARD
- SLC16A1
- AHR
- PTGS2
- PTH1R
- RXRA
- SAMHD1
- SELE
- SELL
- SELP
- SLCO1B3
- SLCO1B1
- ABCC2
- VDR
- UGT2B15
- UGT1A8
- UGT1A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AK1C4
- GABRB2
- GABRD
- GABRE
- GABRG1
- GABRG2
- GABRG3
- GABRP
- GABRQ
- GCR
- GLI3
- GSK3A
- GSK3B
- HDAC9
- HTT
- KSYK
- MAOA
- MAOB
- NF2L2
- NR1I2
- NSD2
- PRGR
- RARA
- SMAD2
- SMCA2
- SMN
- STK16
- GABRB3
- GABRB1
- CCNB1
- GABRA6
- CCNB2
- CCNB3
- CDK1
- CDK5
- CDK5R1
- CLK1
- CP19A
- CP1A1
- CP1A2
Cross-references
Synonyms
- 5,7-Dihydroxyflavone
- Chrysine
- 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one
- Crysin
- 5,7-dihydroxy-2-phenylchromen-4-one
- 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-phenyl-
- UNII-3CN01F5ZJ5
- NSC 407436
- FLAVONE, 5,7-DIHYDROXY-
- EINECS 207-549-7
- NSC407436
- 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
- CHEMBL117
- 5,7-Dihydroxy-2-phenyl-chromen-4-one
- BRN 0233276
- 3CN01F5ZJ5
- CHEBI:75095
- RTIXKCRFFJGDFG-UHFFFAOYSA-N
- 5,7-Dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one
- MFCD00006834
- Chrysin, 99+%
- CAS-480-40-0
- DTXCID902396
- 5,7-dihydroxy flavone
- RefChem:5686
- Chrysin 99+%
- Chrysinic acid
- SMR000112318
- SR-01000765660
- Chrysinic acid;
- 3ebo
- 4des
- 5,7-flavonone
- Chrysin (Standard)
- 5,7-diOH-Flavone
- Flavone,7-dihydroxy-
- Chrysin, 97%
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