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NELFINAVIR
SynDRA canonical compound SYN0000959 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP3A4 |
|---|
| Mechanism of action | HIV protease inhibitor |
|---|
| Indication | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP3A4
- CYP2C9
- CYP3A7
- CYP1A2
- CYP2B6
- CYP2C19
- CYP2D6
- OPRD1
- OPRK1
- OPRM1
- PGR
- SLC6A2
Mechanisms of action (all sources)
- protease inhibitor
- pol INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALB
- ABCB11
- PDE3A
- NR3C1
- NR1H4
- NPY2R
- NPY1R
- NFE2L2
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK1
- PDE5A
- MAOA
- KDR
- KCNH2
- IDH1
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- PDE4A
- PPARD
- HMGCR
- SLCO1A2
- VDR
- THRB
- TDP1
- TBXA2R
- TACR1
- SMN1
- SMAD3
- SLCO2B1
- SLCO1B3
- SLCO1B1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ACM4
- ACM5
- CP3A4
- ESRRA
- IDHC
- KCMB1
- MDM2
- MDM4
- NF2L2
- PPP1CA
Drug classes
- HIV Protease Inhibitors
- Protease Inhibitor
- Cytochrome P450 3A Inhibitors
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Enzyme Inhibitors
- Protease Inhibitors
- Viral Protease Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- VIRACEPT
- Viracept
- viracept
- nelfinavir mesylate
- nelfinavir mesilate
- NSC-747167
- VRX496
- Nelfinavir [INN:BAN]
- AG1343
- UNII-HO3OGH5D7I
- AG 1343
- C32H45N3O4S
- NELFINAVIR MESYLATE AG1343
- Viracept (TN)
- HO3OGH5D7I
- CHEBI:7496
- NLF
- 1UN
- NFV
- Nelfinavir Monomethane Sulfonate
- AG1346
- Nelfinavir (INN)
- Nelfinavir [BAN:INN]
- AG1343 (*Mesylate salt*)
- Viracept (TM)(*Mesylate salt*)
- Met-SDF-1beta & Nelfinavir
- Met-Stromal Cell-derived Factor-1beta (Human) & Nelfinavir
- NSC 747167
- nelfinavirum
- RefChem:57161
- DTXCID3015080
- J05AE04
- AG-1343
- AG1341
- MFCD01938163
- NELFINAVIR [INN]
- SMR000596515
- NCGC00090782-03
Reported adverse events
- Nausea
- Rash
- Flatulence
- Leukopenia
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