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INDINAVIR ANHYDROUS
SynDRA canonical compound SYN0000957 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CYP3A5 |
|---|
| Mechanism of action | HIV protease inhibitor |
|---|
| Indication | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP3A4
- CYP3A5
- CYP3A7
- HIV PR
- HIV-1 protease
- SLC47A1
- SLC47A2
- TACR2
- TBXAS1
- gag-pol
- pol
- protease
Mechanisms of action (all sources)
- protease inhibitor
- HIV PR INHIBITOR
- pol INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- ABCB11
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KDM4A
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- NPY2R
- ABCB1
- NR3C1
- SIGMAR1
- TDP1
- TBXA2R
- TACR1
- SLCO2B1
- SLCO1B3
- SLCO1B1
- SLCO1A2
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP19A
- CP2D6
- CP3A4
- CP3A7
- KCMB2
- TNNC1
- TNNI3
- TNNT2
Drug classes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Enzyme Inhibitors
- HIV Protease Inhibitors
- Protease Inhibitors
- Viral Protease Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- CRIXIVAN
- indinavir
- indinavir sulphate
- crixivan
- indinavir sulfate
- Indinavir
- Crixivan
- IDV
- Indinavir [USAN]
- L-735524
- Crixivan (TM)
- Crixivan (TN)
- L-735 524
- MK-639
- Propolis+Indinavir
- RS-253
- L-735,524
- Indinavir, Sulfate (1:1)
- Indinavir (*1:1 Sulfate salt*)
- INDINAVIR
- Indinavir system suitability
- 5W6YA9PKKH
- indinavir system suitability (usp-rs)
- 9MG78X43ZT
- indinavir (usp-rs)
- Indinavir monohydrate
- Compound J
- CHEBI:44032
- indinavirum
- RefChem:790918
- DTXCID2023802
- J05AE02
- L735 524
- L 735 524
- MK 639
- MK639
- C36H47N5O4
- Indinavir [USAN:INN:BAN]
- UNII-9MG78X43ZT
Reported adverse events
- Abdominal pain
- Asthenia
- Back pain
- Cough
- Dizziness
- Dyspepsia
- Dysuria
- Headache
- Hypersensitivity
- Jaundice
- Malaise
- Nausea
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