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BENZOCAINE
SynDRA canonical compound SYN0000908 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | SCN10A | SCN9A |
|---|
| Mechanism of action | sodium channel blocker |
|---|
| Indication | first-aid antiseptic |
|---|
| Disease area | infectious disease |
|---|
All known targets
- SCN10A
- SCN9A
- SCN11A
- SCN1A
- SCN2A
- SCN3A
- SCN4A
- SCN5A
- SCN7A
- SCN8A
Mechanisms of action (all sources)
- sodium channel blocker
- SCN1A BLOCKER
- SCN2A BLOCKER
- SCN3A BLOCKER
- SCN4A BLOCKER
- SCN8A BLOCKER
- SCN9A BLOCKER
- SCN11A BLOCKER
- SCN10A BLOCKER
- SCN7A BLOCKER
- SCN5A BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- ABCB1
- LMNA
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- GMNN
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- USP1
- TBXAS1
- TBXA2R
- TARDBP
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2C9
- CP2CJ
- CP3A7
- ESRRA
- MDR1
- PPARG
Drug classes
- Anesthetics
- Anesthetics, Local
- Central Nervous System Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
- Standardized Chemical Allergen
ATC classes
- D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- N01B · ANESTHETICS, LOCAL
- R02A · THROAT PREPARATIONS
Cross-references
Synonyms
- Alpha-caine
- Americaine
- Anbesol
- BOIL-EASE
- Benz-O-Sthetic
- Benzo-Jel
- Benzodent
- Brace Relief
- Dermoplast
- Hurricaine
- Lanacane
- Orajel
- norcaine
- 4-Carbethoxyaniline
- benzocaine hydrobromide
- benzocaine hydrochloride
- benzocaine HCl
- benzocaine methanesulfonate
- ethyl aminobenzoate
- parathesin
- americaine
- benzocaine formate
- Benzocaina
- Ethyl aminobenzoate
- Anaesthesin
- Benzocainum
- Ethyl p-aminobenzoate
- Ethyl paba
- Ethyl para-amino benzoate
- Flavamed
- Norcaine
- Parathesin
- Parathesine
- Subcutin
- AR-01
- AR01
- NSC-41531
- NSC-4688
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