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INDOPROFEN
SynDRA canonical compound SYN0000888 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Prostanoid receptor antagonist |
|---|
All known targets
- PTGS1
- PTGS2
- CXCR1
- CXCR2
- FABP1
- Fabp1
- PKM
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- Prostanoid receptor antagonist
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
- FABP1 INHIBITOR
- CXCR2 INHIBITOR
- CXCR1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- HDAC6
- ESR1
- ABCC4
- MC3R
- NR1I2
- NPY1R
- NPC1
- NFE2L2
- MLNR
- MBNL1
- HTR2A
- MAOA
- KCNH2
- IDH1
- HTT
- HTR3A
- HTR2C
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- TDP1
- TBXA2R
- SMN1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SAMHD1
- RAB9A
- PTH1R
- PGR
- PDE4D
- PDE3A
- HTR2B
- HSPA5
- HTR1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM4
- MDR1
- STAT1
- SMN
- SENP8
- SENP7
- SENP6
- NFKB1
- HS90A
- AHR
- CP19A
- CASP9
- CASP5
- CASP4
- CASP3
- CASP1
- TF65
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- isindone
- racemic indoprofen
- Indoprofene
- Indoprofeno
- Bor-ind
- Flosin
- Flosint
- Isindone
- Praxis
- Reumofene
- K-4277
- NSC-757065
- Dexindoprofen
- UNII-004T8726AU
- 004T8726AU
- (+)-indoprofen
- Dexindoprofenum
- Dexindoprofene
- Dexindoprofeno
- Dexindoprofen [INN]
- Dexindoprofenum [INN-Latin]
- Dexindoprofene [INN-French]
- Dexindoprofeno [INN-Spanish]
- Indoprofen (+)-
- EINECS 258-351-2
- AC1Q5QZO
- AC1L2A9M
- ZINC391
- SCHEMBL286896
- (+)-(S)-4-(1-Oxo-2-isoindolinyl)hydratropasaeure
- CHEMBL2106252
- AJ-07888
- (+)-(S)-p-(1-Oxo-2-isoindolinyl)hydratropic acid
- UNII-CPE46ZU14N component RJMIEHBSYVWVIN-NSHDSACASA-N
- 2-(4-(1-oxoisoindolin-2-yl)phenyl)propanoic acid
- Indoprofenum
- 2-(4-(1-Carboxyethyl)phenyl)-1-isoindolinone
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