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NITROFURANTOIN
SynDRA canonical compound SYN0000886 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | DNA inhibitor |
|---|
| Indication | pyelonephritis | urinary tract infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- ESR1
- MMP9
- MC4R
- MC5R
- MDH1
- MLNR
- MMP1
- NFE2L2
- MBNL1
- NPY1R
- NPY2R
- NR1H4
- NR1I2
- NR3C1
- OPRD1
- MC3R
- ABCC2
- HTR1A
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4E
- KCNH2
- IDH1
- HTR6
- HTR3A
- HTR2C
- HTR2B
- OPRK1
- OPRM1
- PDE3A
- SLC29A1
- USP1
- TSHR
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP19A
- CP2CJ
- CP3A7
- ESRRA
- GLI3
- HCRTR1
- MDM2
- MDR1
- MLLT3
- NF2L2
- PRMT1
- TP53
- UBP1
Drug classes
- Nitrofuran Antibacterial
- Anti-Bacterial Agents
- Anti-Infective Agents
- Anti-Infective Agents, Urinary
ATC classes
- J01X · OTHER ANTIBACTERIALS
Cross-references
Synonyms
- FURADANTIN
- FURALAN
- Furadantin
- IVADANTIN
- MACROBID
- MACRODANTIN
- Macrobid
- Macrodantin
- NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS)
- NITROFURANTOIN MACROCRYSTALLINE
- nitrofurantoin sodium
- furadantin
- furadantoin
- nitrofurantoin, macrocrystalline
- nitrofurantoin monohydrate
- Nitrofurantoin, macrocrystalline
- Nitrofurantoine
- Nitrofurantoina
- Nitrofurantoin anhydrous
- Nitrofurantoin macrocrystal
- Nitrofurantoin, macrocrystals
- Nitrofurantoinum anhydrous
- NSC-2107
- NSC-44150
- Berkfurin
- Ceduran
- Dantafur
- Furalan
- Genfura
- Nitrofurantoin (monohydrate/macrocrystals)
- Nitrofurantoin component of macrobid
- Nitrofurantoin component of macrobid , macrocrystalline
- Nitrofurantoin macrocrystalline
- Alfuran
- Benkfuran
- Berkfuran
- Chemiofuran
Reported adverse events
- Asthenia
- Cyanosis
- Hypersensitivity
- Stevens-Johnson syndrome
- Alopecia
- Dizziness
- Pruritus
- Lupus-like syndrome
- Nausea
- Abdominal pain
- Hepatotoxicity
- Malaise
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