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FENBUFEN
SynDRA canonical compound SYN0000857 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
| Indication | pain relief |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- FFAR1
- HTR2C
- MLNR
- MC3R
- LMNA
- KCNH2
- KAT2A
- HTR3A
- HTR2B
- ADORA1
- HTR2A
- HRH3
- HRH2
- HRH1
- HIF1A
- HDAC6
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- RAB9A
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B3
- SMN1
- GHSR
- ACMSD
- ESR1
- CBX1
- ADORA2A
- ADORA3
- ADRA1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CASP1
- CASP3
- CASP4
- CASP5
- CASP9
- CP1A2
- HDAC9
- M3K3
- M4K2
- MDR1
- PADI4
- RARA
- RXRA
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
- M02A · TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
Cross-references
Synonyms
- bufemid
- lederfen
- napanol
- Fenbufene
- CL 82,204
- CL-82204
- NSC-757812
- Cinopal
- Fenbuzip 300
- Fenbuzip 450
- Lederfen 450
- Lederfen cp
- Lederfen f
- Lederfen
- Napanol
- Bufemid
- 4-(4-Biphenylyl)-4-oxobutyric acid
- 3-(4-Phenylbenzoyl)propionic acid
- 3-(4-Biphenylylcarbonyl)propionic acid
- 4-(biphenyl-4-yl)-4-oxobutanoic acid
- gamma-Oxo(1,1'-biphenyl)-4-butanoic acid
- 3-(4-Biphenylcarbonyl)propionic acid
- Cinopol
- Fenbufenum [INN-Latin]
- Fenbufene [INN-French]
- 4-([1,1'-biphenyl]-4-yl)-4-oxobutanoic acid
- CL 82204
- 4-biphenyl-4-yl-4-oxobutanoic acid
- Butyric acid 4-(4-biphenyl)-4-oxo-
- UNII-9815R1WR9B
- 4-oxo-4-(4-phenylphenyl)butanoic a
- Fenbufenum
- NSC 757812
- (1,1'-BIPHENYL)-4-BUTANOIC ACID, gamma-OXO-
- DTXCID703043
- CHEBI:31599
- 4-[1,1'-biphenyl-4-yl]-4-oxobutanoic acid
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