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CLOFIBRATE
SynDRA canonical compound SYN0000850 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | PPARA |
|---|
| Mechanism of action | PPAR receptor agonist |
|---|
| Indication | cholesterol | hyperlipidemia |
|---|
| Disease area | cardiology | endocrinology |
|---|
All known targets
Mechanisms of action (all sources)
- PPAR receptor agonist
- PPARA AGONIST
- Peroxisome proliferator-activated receptor alpha agonist
- LPL ACTIVATOR
- Platelet aggregation inhibitor
- Lipase clearing factor inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- ABCB11
- MMP9
- MAPK3
- MC3R
- MC4R
- MC5R
- MLNR
- MMP1
- MPHOSPH8
- MAPK1
- NPY1R
- NPY2R
- NR3C1
- NTSR1
- OPRD1
- MAPK14
- MAOA
- GHSR
- LCK
- KCNH2
- JUN
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD11B1
- HRH3
- HRH2
- HRH1
- HMGCR
- OPRK1
- OPRM1
- PDE3A
- SLC6A2
- UGT1A8
- UGT1A3
- UGT1A10
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anticholesteremic Agents
- Antimetabolites
- Hypolipidemic Agents
- Lipid Regulating Agents
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Peripheral Nervous System Agents
- Respiratory System Agents
- Antioxidants
- Protective Agents
- Radiation-Sensitizing Agents
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
Cross-references
Synonyms
- ATROMID-S
- ticlobran
- xyduril
- p-chlorophenoxyisobutyric acid ethyl ester
- lipavil
- lipavlon
- lipomid
- liprinal
- miscleron
- misclerone
- Clofibrato
- Chlorfenisate
- Ethyl p-chlorophenoxyisobutyrate
- AY-61123
- ICI-28257
- NSC-79389
- Atromid
- Atromid-s
- Amotril
- Angiokapsul
- Anparton
- Antilipid
- Antilipide
- Apolan
- Arterioflexin
- Arterosol
- Artevil
- Ateculon
- Ateriosan
- Athebrate
- Atheromide
- Atheropront
- Athromidin
- Atrolen
- Atromida
- Atromidin
- Atrovis
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