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DEFEROXAMINE
SynDRA canonical compound SYN0000822 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | chelating agent |
|---|
| Indication | acute iron intoxication | iron overload |
|---|
| Disease area | hematology |
|---|
All known targets
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KDM4A
- KDM4E
- TF
- TET2
- TDP1
- SMN1
- SLCO1B3
- SLCO1B1
- SAMHD1
- POLI
- PLK1
- NFE2L2
- MMP2
- MMP12
- MDH1
- LMNA
- ATAD5
- CA2
- IDH1
- HDAC6
- HDAC2
- GNAS
- GMNN
- GLS
- GAA
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- CTRC
- CBX1
- TOP2A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- ESRRA
- GEMI
- GNAO
- KSYK
- MDR1
- NSD2
- RGS16
- RGS19
- RGS4
- RGS7
- RGS8
- SENP8
- SYK
- TP53
Drug classes
- Iron Chelating Activity
- Iron Chelator
- Chelating Agents
- Iron Chelating Agents
- Sequestering Agents
- Siderophores
- Contrast Media
- chelating agent
ATC classes
- V03A · ALL OTHER THERAPEUTIC PRODUCTS
Cross-references
Synonyms
- DEFEROXAMINE MESYLATE
- DESFERAL
- Desferal
- deferoxamine mesylate
- deferoxamin
- desferrioxamine
- desferrioxamine mesilate
- deferoxamine mesilate
- desferrioxamine mesylate
- Desferrioxamine
- Deferoxamina
- Desferoxamine b
- Desferrioxamine b
- Dfo-b
- NSC-527604
- Deferoxamine Mesylate
- deferoxamine-mesylate
- DESFERRIOXAMINE
- J06Y7MXW4D
- desferrioxamine-B
- Deferrioxamine
- Deferrioxamine B
- Deferoxamin
- Deferoxamine B
- Deferoxaminum
- Desferin
- DFOM
- Desferan
- Desferex
- Desferral
- Desferrin
- N-Benzoylferrioxamine B
- DFOA
- Ferrioxamine B, N-benzoyl-
- NSC527604
- CHEBI:4356
- Deferoximine
- Desferioximine
Reported adverse events
- Abdominal discomfort
- Acute respiratory distress syndrome
- Dysuria
- Hypersensitivity
- Infection
- Injection site reaction
- Mucormycosis
- Muscle spasms
- Tachycardia
- Growth retardation
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