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BENZNIDAZOLE
SynDRA canonical compound SYN0000821 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | DNA synthesis inhibitor |
|---|
| Indication | Chagas disease |
|---|
| Disease area | infectious disease |
|---|
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- HTR2A
- MC3R
- MAOA
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- HTR1A
- FECH
- HRH3
- HRH2
- HRH1
- HMBS
- HDAC6
- GMNN
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4A
- PDE4D
- PGR
- PTGS1
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- GHSR
- F2
- ADORA1
- ADRB2
- AVPR2
- AVPR1A
- AURKB
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Infective Agents
- Antiparasitic Agents
- Antiprotozoal Agents
- Immunologic Factors
- Immunosuppressive Agents
- Mutagens
- Noxae
- Trypanocidal Agents
ATC classes
- P01C · AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
Cross-references
Synonyms
- benznidazol
- benzonidazol
- benzonidazole
- radanil
- Benznidazol
- Benznidazolum
- Benzonidazol
- Radanil
- Rochagan
- NSC-299972
- RO-07-1051
- RO-7-1051
- Benzonidazole
- Benznidazolum;Ro 07-1051
- UNII-YC42NRJ1ZD
- Benznidazolum [INN-Latin]
- Benznidazol [INN-Spanish]
- Ro 71051
- NSC 299972
- Benznidazole [INN]
- CCRIS 2200
- N-Benzyl-2-nitroimidazole-1-acetamide
- YC42NRJ1ZD
- Imidazole-1-acetamide, N-benzyl-2-nitro-
- Ro-7-1051
- N-benzyl-2-(2-nitroimidazol-1-yl)acetamide
- N-Benzyl-2-nitroimidazol-1-yl-acetamide
- N-benzyl-2-nitro-1-imidazoleacetamide
- NSC299972
- DTXCID7026570
- CHEBI:133833
- RefChem:58523
- P01CA02
- MFCD00243089
- MMV688773
- NCGC00166238-01
- Ro 07-1051;Ro 71051
Reported adverse events
- Abdominal pain
- Agranulocytosis
- Amnesia
- Carcinogenicity
- Depression
- Disorientation
- Dizziness
- Erythema
- Erythema multiforme
- Fatigue
- Headache
- Hypersensitivity
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