← SynDRA
YOHIMBINE
SynDRA canonical compound SYN0000803 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HTR2B |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
| Indication | bradycardia | cardiac arrythmia |
|---|
| Disease area | cardiology |
|---|
All known targets
- HTR1D
- ADRA2B
- HTR1B
- HTR1A
- ADRA2C
- HTR2B
- ADRA2A
- HTR1F
- HTR1E
- HTR7
- HTR5A
- DRD2
Mechanisms of action (all sources)
- Adrenergic receptor antagonist
- ADRA2A ANTAGONIST
- ADRA2B ANTAGONIST
- ADRA2C ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ABCB1
- MC3R
- OPRK1
- OPRD1
- NTSR1
- NR3C1
- NPY2R
- NPY1R
- NPSR1
- MTOR
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MAPK3
- OXTR
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KDM4A
- KAT2A
- HTR3A
- HRH3
- HRH2
- HRH1
- HPGD
- HMGCR
- OPRM1
- PDE3A
- HCRTR2
- PDE4A
- THRB
- TDP1
- TBXAS1
- TBXA2R
- TACR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Adrenergic Agents
- Adrenergic alpha-2 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Mydriatics
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Urological Agents
ATC classes
Cross-references
Synonyms
- yohimbin
- quebrachin
- quebrachine
- yohimbine hydrochloride
- yohimbine HCl
- Yohimbinum
- APHRODINE
- Actibine
- Aphrodyne
- Aphrosol
- Corynine
- Johimbin
- Quebrachin
- Quebrachine
- Thybine
- Yocon
- Yohimar
- Yohimbin
- Yohimex
- Yoman
- Yovital
- Dayto himbin
- Yohimbic acid methyl ester
- Baron-X
- Trans-Quinolizidine yohimbine
- Yohimbine (DCF)
- Methyl 17alpha-hydroxyyohimban-16alpha-carboxylate
- Yohimbol-16alpha-carboxylic acid, methyl ester (6CI)
- Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.
- Methyl (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylate
- Yohimban-16alpha-carboxylic acid, 17alpha-hydroxy-, methyl ester (8CI)
- Yohimban-16-alpha-carboxylic acid, 17-alpha-hydroxy-, methyl ester
- Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)-(9CI)
- Yohimban-16-.alpha.-carboxylic acid, 17-.alpha.-hydroxy-, methyl ester
- (+)-Yohimbin
- (+)-Yohimbine
- (16alpha,17alpha)-17-Hydroxy-yohimban-16-carboxylic acid methyl ester
- (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester
Look up YOHIMBINE in the interactive SynDRA portal →