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CLOBENPROPIT
SynDRA canonical compound SYN0000776 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HRH4 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH1 ANTAGONIST
- HRH2 ANTAGONIST
- HRH3 ANTAGONIST
- HRH4 PARTIAL AGONIST
- HRH4 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALOX15B
- APP
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- CYP46A1
- GBA1
- HDAC6
- TDP1
- TP53
- USP1
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
Drug classes
Cross-references
Synonyms
- Vuf 9153
- UNII-RKU631JF4H
- S-(3-(4(5)-Imidazolyl))propyl-N-(4-chlorobenzyl)isothiourea
- CHEBI:64177
- RKU631JF4H
- 3-(1h-imidazol-5-yl)propyl n'-(4-chlorobenzyl)carbamimidothioate
- 3-(1H-imidazol-4-yl)propyl ((4-chlorophenyl)methyl)carbamimidothioate
- Carbamimidothioic acid, ((4-chlorophenyl)methyl)-, 3-(1H-imidazol-4-yl)propyl ester
- 3-(1H-imidazol-4-yl)propyl N-(4-chlorobenzyl)carbamimidothioate
- Carbamimidothioic acid,N-[(4-chlorophenyl)methyl]-, 3-(1H-imidazol-5-yl)propyl ester
- RefChem:127006
- DTXCID1023738
- C14H17ClN4S
- MFCD00467655
- 3-(1H-Imidazol-5-yl)propyl 4-chlorobenzylcarbamimidothioate
- VUF9153
- Clobenpropit free base
- Tocris-0752
- SCHEMBL49050
- MLS001424295
- GTPL1223
- orb1705982
- SCHEMBL8312286
- SCHEMBL19733457
- BDBM22541
- UCAIEVHKDLMIFL-UHFFFAOYSA-N
- HMS2052B07
- HMS3394B07
- AAA30301
- BDBM50214615
- PDSP1_000537
- PDSP2_000535
- AKOS025405026
- CCG-101167
- NC00417
- NCGC00024770-01
- NCGC00024770-02
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