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NEOSTIGMINE
SynDRA canonical compound SYN0000756 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | ACHE |
| Mechanism of action | Acetylcholinesterase inhibitor |
| Indication | myasthenia gravis |
| Disease area | neurology/psychiatry |
All known targets
Mechanisms of action (all sources)
- Acetylcholinesterase inhibitor
- ACHE INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB1
- MAPK14
- NR3C1
- NPY2R
- NPY1R
- NPSR1
- NFE2L2
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MBNL1
- MAPK3
- MAPK1
- HRH1
- MAOA
- LMNA
- LIPA
- LCK
- KDR
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SMAD3
- SLCO1B3
- SLCO1B1
- SLC6A4
Drug classes
- Cholinesterase Inhibitors
- Cholinergic Agents
- Enzyme Inhibitors
- Neurotransmitter Agents
- Parasympathomimetics
- Peripheral Nervous System Agents
- Cholinesterase Inhibitor
ATC classes
- S01E · ANTIGLAUCOMA PREPARATIONS AND MIOTICS
- N07A · PARASYMPATHOMIMETICS
Cross-references
Synonyms
- BLOXIVERZ
- Bloxiverz
- NEOSTIGMINE METHYLSULFATE
- PREVDUO
- Prevduo
- eustigmin
- eustigmine
- prostigmin
- prostigmine
- vagostigmine
- neostigmine methylsulfate
- neostigmine bromide
- Miostin
- Neostigmine (cation)
- Neostigmine cation
- Neostigmine hydroxide
- Neostigmine ion
- Eustigmin
- Eustigmine
- Intrastigmina
- Juvastigmin
- Neostigmin
- Neostigminum
- Prostigmin
- Prostigmine
- Prozerin
- Sulfonatooxymethane
- Synstigmin
- Syntostigmine
- Vagostigmin
- Vagostigmine
- Neostigmine [BAN]
- Neostigmine omega
- M-Trimethylammoniumphenyldimethylcarbamate
- Neostigmine (BAN)
- Prostigmin (TN)
- Vagostigmin (TN)
- [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium
Reported adverse events
- Hypersensitivity
- Bradycardia
- Bronchospasm
- Cardiac arrest
- Dizziness
- Dry mouth
- Arthralgia
- Insomnia
- Rash
- Incision site complication
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