← SynDRA

MITOMYCIN

SynDRA canonical compound SYN0000737 — structure-anchored drug synonym record

All known targets

• IDO1

Mechanisms of action (all sources)

• DNA alkylating agent
• DNA synthesis inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ESR2
• ESR1
• ABCB1
• KCNH2
• MMP9
• MMP1
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAPK1
• MAOA
• LCK
• HTR6
• NPY1R
• HTR2C
• HTR2B
• HTR2A
• HTR1A
• HRH3
• HRH2
• HRH1
• HMGCR
• HDAC6
• NFE2L2
• NPY2R
• FYN
• NR3C1
• TDP1
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SLC6A4
• SLC6A3
• SLC6A2
• SIGMAR1
• PTPRC
• PTGS2

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ALAT2
• ANDR
• SYK
• STK33
• RARA
• PRGR
• PPARG
• PPARD
• NR1H4
• NF2L2
• KSYK
• GLI3
• GCR
• ESRRA
• CP3A7
• CP2D6
• CP1A2
• CP19A
• CASP7
• CASP3
• ATXN2
• TP53

Drug classes

• Alkylating Activity
• Alkylating Drug
• Alkylating Agents
• Antibiotics, Antineoplastic
• Antineoplastic Agents
• Cross-Linking Reagents
• Enzyme Inhibitors
• Indicators and Reagents
• Noxae
• Nucleic Acid Synthesis Inhibitors

ATC classes

• L01D · CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES

Cross-references

• PubChem CID: 5746
• ChEMBL: CHEMBL105
• DrugBank: DB00305
• ChEBI: CHEBI:27504
• KEGG: D00208
• RxNorm: 632
• Wikipedia: Mitomycin_C
• TTD: D0Y0GH

Synonyms

• JELMYTO
• Jelmyto
• MITOSOL
• MITOZYTREX
• MUTAMYCIN
• Mitosol
• Mutamycin
• ZUSDURI
• Zusduri
• mutamycin
• Mitomycin C
• Mitomycine
• Mitomicina
• Mitomycin-c
• Ametycine
• Mitocin-c
• Muamycin
• UGN-102
• NSC-26980
• UGN-101
• Mitozytrex
• Mytozytrex
• Mitomycin-C
• Mitocin C
• Ametycin
• Mitomycinum
• Mytomycin
• Mitomycinum C
• Mitomycins
• Mitamycin
• MMC
• Mitomycyna C
• 7-Amino-9alpha-methoxymitosane
• NSC 26980
• Mitomycyna C [Polish]
• Mito-C
• Mit-C

Reported adverse events

• Bone marrow suppression
• Rash
• Thrombocytopenia
• Bladder fibrosis
• Cellulitis
• Extravasation
• Headache
• Malaise
• Stomatitis
• Abdominal pain
• Cataract
• Chills