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PHENYL BIGUANIDE
SynDRA canonical compound SYN0000732 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HTR3A | HTR3B |
|---|
| Mechanism of action | serotonin receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- HTR3A AGONIST
- HTR3B AGONIST
- serotonin receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALOX15
- HDAC6
- SLCO1B3
- SLCO1B1
- RGS4
- PTH1R
- POLI
- NFKB1
- LMNA
- EHMT2
- APEX1
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- BLM
- ARSA
- TAAR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2CJ
- HTR3C
- HTR3D
- HTR3E
- SMAD3
Drug classes
- Analgesics
- Hypoglycemic Agents
- Serotonin Receptor Agonists
Cross-references
Synonyms
- 1-phenylbiguanide
- phenylbiguanide
- Phenyldiguanide
- Phenylguanide
- phenyl diguanide
- N-Phenyl-N'-guanylguanidine
- N-phenylimidodicarbonimidic diamide
- Biguanide, phenyl-
- Imidodicarbonimidic diamide, N-phenyl-
- UNII-W8PKA3T2I3
- BIGUANIDE, 1-PHENYL-
- C8H11N5
- N-Phenyl-imidocarbonimidic diamide
- EINECS 202-998-5
- W8PKA3T2I3
- CHEMBL13791
- CHEBI:75377
- P 1426
- Imidodicarbonimidicdiamide, N-phenyl-
- 1-(diaminomethylidene)-2-phenylguanidine
- SR-01000075565
- N-phenylbiguanide
- N'-phenylbiguanide
- 1-PHENYLBIGUANIDE
- Phenylbiguanide
- 1-Phenylbiguanide
- RefChem:172948
- DTXCID6066999
- MFCD00179077
- 1-carbamimidamido-N-phenylmethanimidamide
- N-Phenyliminodicarbonimidic Diamide
- Spectrum_000472
- Spectrum_001460
- Tocris-0969
- Lopac-P-120
- Spectrum2_001190
- Spectrum3_001604
- Spectrum4_000058
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