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HYDROQUINONE
SynDRA canonical compound SYN0000691 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TYR |
|---|
| Mechanism of action | melanin inhibitor |
|---|
| Indication | dyschromia |
|---|
| Disease area | dermatology |
|---|
All known targets
- TYR
- CA1
- Ca13
- ache
- PPO2
- ITGB3
- ITGA2B
- Ca15
- CA9
- CA12
- CA5B
- CA5A
Mechanisms of action (all sources)
- melanin inhibitor
- TYR INHIBITOR
- Tyrosinase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AHR
- ALDH1A1
- NFE2L2
- NFKB1
- NPC1
- NR1H4
- NR3C1
- PIN1
- PMP22
- PPARD
- PTGS2
- RAB9A
- RECQL
- RGS4
- RORC
- RXRA
- SIRT1
- SLCO1B1
- SLCO1B3
- TDP1
- THPO
- THRB
- UGT1A10
- MTOR
- MPHOSPH8
- MAPT
- EHMT2
- ALOX15
- AR
- ARSA
- ATAD5
- ATXN2
- BLM
- CBX1
- CXCL8
- CYP3A4
- ESR1
- LMNA
- FEN1
- GLS
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADCY9
- NR1I2
- SYK
- RARA
- PRGR
- PHGDH
- PE2R2
- NTMT1
- NTM1A
- NSD2
- NF2L2
- CP19A
- KSYK
- HTT
- GSTO1
- GPR151
- GLSK
- GLI3
- FUMH
- ESRRA
- TPO
Drug classes
- Antioxidants
- Mutagens
- Noxae
- Protective Agents
- Radiation-Protective Agents
- Melanin Synthesis Inhibitors
- Melanin Synthesis Inhibitor
ATC classes
- D11A · OTHER DERMATOLOGICAL PREPARATIONS
Cross-references
Synonyms
- Neova Complex HQ Plus
- TRI-LUMA
- 1,4-Benzenediol
- benzene-1,4-diol
- idrochinone
- CHEBI:17594
- CHEMBL537
- NCI-C55834
- NSC-9247
- Black and white bleaching cream
- Eldopaque forte
- Eldoquin forte
- Hydroquinone component of tri-luma
- Solaquin forte
- 1,4-benzenediol
- Benzene-1,4-diol
- 1,4-Dihydroxybenzene
- Quinol
- p-Benzenediol
- p-Hydroxyphenol
- p-Hydroquinone
- 4-Hydroxyphenol
- Eldoquin
- Benzoquinol
- p-Dihydroxybenzene
- hydroquinol
- Eldopaque
- Phiaquin
- p-Dioxybenzene
- Hydroquinole
- Dihydroquinone
- Tecquinol
- Idrochinone
- Benzohydroquinone
- Tequinol
- Hidroquinone
- Arctuvin
- Dihydroxybenzene
Reported adverse events
- Acne
- Erythema
- Papule
- Pruritus
- Rash
- Rosacea
- Telangiectasia
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