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CIRAZOLINE
SynDRA canonical compound SYN0000674 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | ADRA1A |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
All known targets
- ADRA1A
- ADRA1B
- ADRA1D
- ADRA2C
Mechanisms of action (all sources)
- Adrenergic receptor agonist
- ADRA1A FULL AGONIST
- ADRA1B PARTIAL AGONIST
- ADRA1D FULL AGONIST
- ADRA2C AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2A
- ADRA2B
- NISCH
- HTR1A
- THRB
- THPO
- TDP1
- RGS4
- LMNA
- KCNH2
- HSD17B10
- HDAC6
- GMNN
- GALC
- EHMT2
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- CBX1
- ARSA
- APEX1
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP1A2
- CP2D6
- CREB1
- DRD2
- GLI3
- THB
Drug classes
- Adrenergic alpha-1 Receptor Agonists
- Nasal Decongestants
- Vasoconstrictor Agents
Cross-references
Synonyms
- Cirazolina
- Ld-3098
- Cirazoline [INN]
- Cirazolinum [INN-Latin]
- Cirazolina [INN-Spanish]
- UNII-QK318GVY3Y
- LD 3098
- QK318GVY3Y
- CHEMBL13852
- NCGC00015196-04
- 2-((o-Cyclopropylphenoxy)methyl)-2-imidazoline
- DSSTox_CID_25131
- DSSTox_RID_80692
- DSSTox_GSID_45131
- Cirazolinum
- 1H-Imidazole, 2-((2-cyclopropylphenoxy)methyl)-4,5-dihydro-
- 2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole
- CAS-59939-16-1
- Tocris-0888
- Lopac-C-223
- AC1L1EEZ
- Lopac0_000354
- KBioGR_000306
- BSPBio_001586
- KBioSS_000306
- GTPL515
- 2-(2'-cyclopropylphenoxymethyl)imidazoline hydrochloride
- DTXCID2025131
- 2-((2-cyclopropylphenoxy)methyl)-4,5-dihydro-1H-imidazole
- RefChem:126334
- 1H-Imidazole, 2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-
- SCHEMBL126496
- orb1740449
- SCHEMBL29430417
- CHEBI:92950
- KBio2_000306
- KBio2_002874
- KBio2_005442
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