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BMY-7378
SynDRA canonical compound SYN0000666 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HTR1A |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
All known targets
- ADRA1A
- ADRA1B
- ADRA1D
- HTR1A
Mechanisms of action (all sources)
- Serotonin receptor antagonist
- Adrenergic receptor antagonist
- HTR1A PARTIAL AGONIST
- ADRA1A ANTAGONIST
- ADRA1B ANTAGONIST
- ADRA1D ANTAGONIST
- ADRA1D INHIBITOR
- ADRA1A INHIBITOR
- HTR1A INHIBITOR
- ADRA1B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- ALDH1A1
- HDAC6
- THPO
- TDP1
- RGS4
- POLI
- LMNA
- KDM4A
- KCNH2
- GLS
- CYP1A2
- FEN1
- EHMT2
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1A
- ADA1A
- ADA1B
- ADA1D
- CP1A2
- DRD3
- NTM1A
- PA2G3
Cross-references
Synonyms
- UNII-08EI0K81OL
- CHEMBL13647
- 08EI0K81OL
- 8-(2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl)-8-azaspiro[4.5]decane-7,9-dione
- BMY7378
- 8-(2-(4-(2-Methoxyphenyl)-1-piperazinyl)ethyl)-8-azaspiro(4.5)decane-7,9-dione
- 8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione
- 8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione
- 8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione
- 8-Azaspiro(4.5)decane-7,9-dione, 8-(2-(4-(2-methox
- RefChem:914474
- BMY 7378 free base
- Tocris-1006
- GTPL9
- Lopac-B-134
- BMY 7378 (free base)
- Lopac0_000206
- orb3028976
- SCHEMBL6017145
- SCHEMBL32690868
- CHEBI:92539
- EX-A2035A
- AYYCFGDXLUPJAQ-UHFFFAOYSA-N
- HMS3742M05
- BDBM50026917
- CCG-204301
- SB19517
- SDCCGSBI-0050194.P002
- NCGC00015126-01
- NCGC00015126-02
- NCGC00015126-03
- NCGC00015126-04
- NCGC00015126-05
- NCGC00015126-06
- NCGC00015126-08
- NCGC00024935-01
- NCGC00024935-02
- NCGC00024935-03
- HY-116982
Look up BMY-7378 in the interactive SynDRA portal →