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SU-11652
SynDRA canonical compound SYN0000663 — structure-anchored drug synonym record
| Primary target(s) | PDGFRB |
|---|
| Mechanism of action | Tyrosine kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- tyrosine kinase inhibitor
- PDGFRB INHIBITOR
- PDGFRA INHIBITOR
- FLT1 INHIBITOR
- KDR INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PIM1
- SLK
- CSNK1G3
- SYK
- KIT
- PAK4
- NEK2
- EGFR
- PAK6
- FGFR1
- STK16
- MELK
- CLK1
- PLK2
- PRKAA2
- PLK1
- PKN2
- PIM3
- PLK3
- PLK4
- ABL1
- PRKACA
- PIM2
- PRKCB
- PRKCD
- PRKCE
- PRKCG
- PRKCH
- PRKCI
- PRKCQ
- PRKCZ
- PRKD1
- PRKD2
- PRKG1
- PRKX
- PRKCA
- PDPK1
- PHKG2
- PTK2B
- MARK2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- KC1G1
- KSYK
- M3K5
- NSD2
- NTM1A
- NTMT1
- PGFRB
- VGFR2
Cross-references
Synonyms
- SU11652
- 5-[(Z)-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
- UNII-1C7AZL970U
- CHEMBL13485
- 1C7AZL970U
- 5-[(E)-(5-Chloro-2-Oxo-1,2-Dihydro-3h-Indol-3-Ylidene)methyl]-N-[2-(Diethylamino)ethyl]-2,4-Dimethyl-1h-Pyrrole-3-Carboxamide
- 5-{[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
- AC1NS62M
- SU11248 analog 12c
- GTPL6043
- BDBM4815
- SCHEMBL2114096
- CHEBI:132084
- RefChem:186189
- DTXCID40881794
- C22H27ClN4O2
- orb3027348
- SCHEMBL29366350
- CHEBI:94073
- HMS3229K21
- EX-A11152
- MFCD09037560
- NSC845834
- AKOS032946687
- CCG-206791
- NSC-845834
- SDCCGSBI-0086711.P004
- SMP2_000033
- NCGC00484848-01
- AS-86748
- DA-78069
- FC160139
- HY-112452
- CS-0046076
- NS00069728
- H55591
- K00239
- T28874
- BRD-K60623809-001-01-2
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