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PROGESTERONE
SynDRA canonical compound SYN0000661 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PGR |
|---|
| Mechanism of action | Progesterone receptor agonist |
|---|
| Indication | amenorrhea | infertility |
|---|
| Disease area | endocrinology | obstetrics/gynecology |
|---|
All known targets
- PGR
- NR3C2
- CATSPER4
- ESR1
- CYP17A1
- TRPC5
- CATSPER3
- CATSPER2
- CATSPER1
- Srd5a1
- P2RX3
- SOAT1
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- CHRM1
- SLC22A1
- SLC22A3
- GPBAR1
- CYP2C9
- NR1I2
- PDE3A
- OPRD1
- OPRM1
- PDE4A
- NR1H4
- NPY2R
- NPY1R
- NPSR1
- NFE2L2
- MMP9
- MMP1
- PDE4D
- MLNR
- MC5R
- PMP22
- MC4R
- HTR2C
- HTR3A
- HTR6
- IDH1
- KCNH2
- KDM4E
- KDR
- LCK
- LMNA
- MAOA
- MAPK1
- MAPK14
- MAPK3
- MAPT
- MC3R
- PDE5A
- PPARG
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACES
- NF2L2
- HNF4G
- IFNG
- KCNJ1
- MCR
- MDR1
- MK01
- NR1H2
- ACM1
- NR4A2
- NR5A2
- RARA
- RARB
- RARG
- RORA
- HNF4A
- GLI3
- GCR
- ESRRA
- ERR3
- CTSR4
- CTSR2
- CTSR1
- CSTA
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- COT1
- ANDR
- AK1C4
- ADA10
- TP53
Drug classes
- Neuromuscular Agents
- Neuromuscular Blocking Agents
- Neuromuscular Nondepolarizing Agents
- Peripheral Nervous System Agents
- Hormones
- Progestins
- Progesterone
- Neurosteroids
ATC classes
- G03D · PROGESTOGENS
- PROGESTOGENS AND ESTROGENS IN COMBINATION
Cross-references
Synonyms
- BIJUVA
- Bijuva
- CRINONE
- Crinone
- ENDOMETRIN
- ESTRADIOL AND PROGESTERONE
- Endometrin
- MILPROSA
- PROGESTASERT
- PROMETRIUM
- Prometrium
- gestone
- gestormone
- glanducorpin
- lugesteron
- lugesterone
- progestan
- progeston
- progestone
- progestron
- progesterol
- syngesterone
- Progesterona
- Progesterone, micronized
- Progesteronum
- NSC-64377
- NSC-9704
- U 3672
- Cyclogest
- Lutigest
- Milprosa
- Prochieve
- Progesta-care
- Progestasert
- Progesterone component of bijuva
- Progestin
- Regumate
Reported adverse events
- Dementia
- TIA
- Cardiovascular disorder
- Cancer
- DVT
- Fatigue
- Headache
- Nausea
- Dizziness
- Vomiting
- Constipation
- Infection
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