PIROXICAM

SynDRA canonical compound SYN0000634 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	PTGS1 \| PTGS2
Mechanism of action	cyclooxygenase inhibitor
Indication	osteoarthritis \| osteoarthritis, rheumatoid arthritis \| rheumatoid arthritis
Disease area	rheumatology

All known targets

PTGS1
PTGS2
Ptgs1
Ptgs2

Mechanisms of action (all sources)

PTGS2 INHIBITOR
Cyclooxygenase inhibitor
PTGS1 INHIBITOR
PTGS1 MODULATOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

AHR
CP1A2
CP2C9
CP2CJ
CP2D6

Drug classes

Cyclooxygenase Inhibitors
Analgesics
Analgesics, Non-Narcotic
Anti-Inflammatory Agents
Anti-Inflammatory Agents, Non-Steroidal
Antirheumatic Agents
Peripheral Nervous System Agents
Sensory System Agents
Enzyme Inhibitors
Nonsteroidal Anti-inflammatory Drug

ATC classes

M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M02A · TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
S01B · ANTIINFLAMMATORY AGENTS

Cross-references

PubChem CID: 54676228
ChEMBL: CHEMBL527
DrugBank: DB00554
ChEBI: CHEBI:8249
KEGG: D00127
RxNorm: 8356
Wikipedia: Piroxicam
TTD: D00IBN

Synonyms

Reported adverse events

Bleeding
GI bleed
Perforation
Ulceration
Elderly
Alopecia
Anxiety
Asthma
Conjunctivitis
Dizziness
Hypersensitivity
Pruritus

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