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INAMRINONE
SynDRA canonical compound SYN0000593 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PDE3A |
|---|
| Mechanism of action | Phosphodiesterase inhibitor |
|---|
| Indication | congestive heart failure |
|---|
| Disease area | cardiology |
|---|
All known targets
- PDE3A
- PDE3B
- PDE4B
- PDE4A
- PDE4C
- PDE4D
- TNF
- TTK
Mechanisms of action (all sources)
- Phosphodiesterase inhibitor
- PDE3A INHIBITOR
- Phosphodiesterase 3A inhibitor
- PDE3B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2B
- ABL1
- MC5R
- MAPK3
- MAPKAPK2
- MAPKAPK5
- MAPT
- MBNL1
- MC3R
- MC4R
- MET
- MAPK1
- MLNR
- MMP1
- MMP9
- MPI
- NPY1R
- NPY2R
- NR1I2
- MAPK14
- MAOA
- OPRD1
- HTR3A
- HRH2
- HRH3
- HSD17B10
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR6
- LYN
- HTT
- INSR
- ITK
- KCNH2
- KDM4E
- LCK
- LMNA
- NR3C1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALAT2
- PIP4K2A
- THB
- TERA
- S10A4
- RPGF4
- RAPGEF4
- PRMT1
- PPM1D
- PLIN5
- PLIN1
- PI4K2A
- CP1A2
- NF2L2
- LOX15
- GSTO1
- G3P
- DLD
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- UBP1
Drug classes
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiotonic Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Membrane Transport Modulators
- Phosphodiesterase 3 Inhibitors
- Phosphodiesterase Inhibitors
- Protective Agents
- Vasodilator Agents
ATC classes
- C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
Cross-references
Synonyms
- AMRINONE LACTATE
- INOCOR
- amrinone
- inamrinone lactate
- cartonic
- cordemcura
- vesistol
- wincoram
- Amrinone
- Amrinona
- Amcoral
- Cartonic
- Cordemcura
- Vesistol
- Wincoram
- C01CE01
- NSC-759805
- WIN-40680
- Inamrinone Lactate
- Inocor
- Amrinonum [INN-Latin]
- Amrinonum
- Amrinona [INN-Spanish]
- 3-Amino-5-(4-pyridinyl)-2(1H)-pyridinone
- WIN 40680
- AWD 08-250
- UNII-JUT23379TN
- CCRIS 3794
- Amrinone lactate
- MLS000069829
- EINECS 262-390-0
- 5-amino-3,4'-bipyridin-6(1H)-one
- BRN 0744819
- SMR000058850
- CHEMBL12856
- JUT23379TN
- Win-40680
- NSC 759805
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