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SEMUSTINE
SynDRA canonical compound SYN0000580 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Mechanism of action | DNA alkylating agent |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- FLT1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HRH2
- HRH1
- HMGCR
- HDAC6
- NR3C1
- OPRD1
- OPRK1
- SLC6A2
- TDP1
- TBXAS1
- TACR2
- TACR1
- SMN1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SIGMAR1
- OPRM1
- SAMHD1
- PTPRC
Drug classes
- Alkylating Agents
- Antineoplastic Agents
- Antineoplastic Agents, Alkylating
- Noxae
ATC classes
Cross-references
Synonyms
- methyl lomustine
- Methyl-CCNU
- Semustina
- Methyl lomustine
- ICIG-1110
- METHYL-CCNU
- NSC-758471
- METHYL CCNU
- 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
- MeCCNU
- N-(2-Chloroethyl)-N'-(4-methylcyclohexyl)-N-nitrosourea
- Semustinum
- Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-
- Lomustine, methyl-
- NSC-95441
- NCI-C04955
- Me CCNU
- 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-urea
- NSC95441
- Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-
- CHEBI:6863
- DTXCID6011603
- 6YY7T1T567
- 1-[2-Chloroethyl]-3-[4-methylcyclohexyl]-1-nitrosourea
- MCCNU
- RefChem:884865
- L01AD03
- trans-Methyl CCNU
- EGU4CMI14D
- NSC 135091
- NCGC00095051-01
- 1-(2-Choroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
- trans-Semustine
- cis-Semustine
- Semustine [USAN:INN]
- Semustinum [INN-Latin]
- Semustina [INN-Spanish]
- cis-Methyl CCNU
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