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SERTINDOLE
SynDRA canonical compound SYN0000577 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Primary target(s) | HTR2C |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
All known targets
- DRD2
- HTR2C
- HTR2A
- ADRA1B
- ADRA1A
- DRD4
- DRD3
- ADRA1D
- HTR1F
- HTR1E
- HTR1D
- HTR1B
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- Serotonin receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- ADRA1A ANTAGONIST
- Adrenergic receptor alpha-1 antagonist
- ADRA1D ANTAGONIST
- ADRA1B ANTAGONIST
- HTR2A ANTAGONIST
- HTR2C ANTAGONIST
- HTR1A ANTAGONIST
- HTR1B ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNA5
- SCN5A
- MLNR
- NR1I2
- OPRK1
- CACNA1C
- CHRM1
- SLC6A2
- SLC6A3
- SLC6A4
- SLC29A1
- SAMHD1
- PTGS2
- MAOA
- PGR
- PDE4D
- PDE3A
- OPRM1
- OPRD1
- NR3C1
- NPY1R
- TBXA2R
- MC3R
- ABCB11
- ADORA1
- HTR3A
- ADORA2A
- ADORA3
- AGTR1
- AVPR1A
- AVPR2
- BDKRB2
- CCKAR
- CCKBR
- CHRM2
- CHRNA4
- CNR1
- EDNRA
- FAAH
- GHSR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1A
- SCN1A
- JUN
- KSYK
- NFKB1
- NSD2
- RARA
- SCN10A
- SCN11A
- SCN2A
- 5HT1B
- SCN3A
- SCN4A
- SCN7A
- SCN8A
- SCN9A
- SYK
- TOR1A
- GLI3
- GCR
- ESRRA
- ESR1
- 5HT1D
- 5HT1E
- 5HT1F
- ACES
- ACM1
- ANDR
- ATXN2
- CACNA1D
- CACNA1F
- CACNA1S
- CASP3
- CASP7
- COT2
- CP2D6
- CP3A7
- TSHR
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- sertindole hydrochloride
- sertindole HCl
- Lu 23-174
- serdolect
- zerdol
- Sertindol
- Serdolect
- Zerdol
- LU-23-174
- Serlect
- SerLect
- Sertindolum
- Sertindole hydrochloride
- Lu-23-174
- S-1991
- SerLect (TN)
- Serdolect (TN)
- Sertindol [INN-Spanish]
- Sertindole [USAN:INN]
- Sertindolum [INN-Latin]
- Sertindole (USAN/INN)
- 1-(2-(4-(5-Chloro-1-(4-fluorophenyl)-1H-indole-3-yl)-1-piperidinyl)ethyl)-2-imidazolidinone
- 1-(2-(4-(5-Chloro-1-(p-fluorophenyl)indol-3-yl)piperidino)ethyl)-2-imidazolidinone
- 1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl)-1-piperidinyl)ethyl)-2-imidazolidinone
- 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one
- 1-[2-[4-[5-Chloro-1-(p-fluorophenyl)indol-3-yl]piperidino]ethyl]-2-imidazolidinone
- 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one
- 1-[2-[4-[5-chloro-1-(4-fluorophenyl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
- GVV4Z879SP
- CHEMBL12713
- CHEBI:9122
- NCGC00181782-01
- NCGC00181782-02
- 1-(2-(4-(5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl)piperidin-1-yl)ethyl)imidazolidin-2-one
- 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-1h-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone
- 2-Imidazolidinone, 1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl)-1-piperidinyl)ethyl)-
- 1-(2-{4-[5-Chloro-1-(p-fluorophenyl)indol-3-yl]piperidino}ethyl)-2-imidazolidinone
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