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HARMAN
SynDRA canonical compound SYN0000521 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | MAOB |
|---|
| Mechanism of action | Monoamine oxidase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Monoamine oxidase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DYRK1A
- TDO2
- NEK6
- PIM2
- PIM1
- PDPK1
- PAK6
- PAK5
- PAK4
- NPSR1
- NFKB1
- NEK7
- ACHE
- PIM3
- MYLK
- MKNK2
- MKNK1
- MELK
- MARK3
- MAPT
- MAPKAPK5
- MAPKAPK3
- MAPKAPK2
- NEK2
- PKN2
- MAPK8
- RPS6KA3
- TOP1
- TDP1
- STK3
- SRPK1
- SLCO1B3
- SLCO1B1
- SGK1
- RPS6KB1
- RPS6KA5
- RPS6KA1
- PLK1
- ROCK2
- RGS4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ATRX
- CP1A2
- KLK7
- GABRQ
- GABRP
- GABRG3
- GABRG2
- GABRG1
- GABRE
- GABRD
- GABRB3
- GABRB2
- GABRB1
- GABRA6
- GABRA5
- GABRA4
- GABRA3
- GABRA2
- GABRA1
- CP3A4
- CP2D6
- NTM1A
Drug classes
Cross-references
Synonyms
- harmane
- HARMANE
- 1-Methyl-9H-pyrido[3,4-b]indole
- Aribine
- Locuturine
- Loturine
- Aribin
- Passiflorin
- 1-Methylnorharman
- Locuturin
- 1-Methyl-beta-carboline
- 9H-Pyrido[3,4-b]indole, 1-methyl-
- 1-methyl-2-carboline
- 9H-Pyrido(3,4-b)indole, 1-methyl-
- 1-Methyl-9H-pyrido(3,4-b)indole
- NSC 54439
- CHEBI:5623
- RefChem:145268
- DTXCID40120059
- 1-Methyl-9H-beta-carboline
- 3-Methyl-4-carboline
- PYRIDOBINDOLE, L-METHYL-
- MFCD00004957
- methylbeta-carboline
- 1-Methyl-.beta.-carboline
- NSC54439
- ST013856
- Passiflorin-13C2,15N
- Zygofabagine
- 1-Methyl-9H-pyrid(3,4-b)indole
- 1-Methyl-9H-pyrid[3,4-b]indole
- CCRIS 6419
- SR-01000075915
- EINECS 207-642-2
- BRN 0143898
- Passiflorine
- UNII-82D6J0535P
- CN9
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