← SynDRA

HISTAMINE

SynDRA canonical compound SYN0000492 — structure-anchored drug synonym record

All known targets

• HRH1
• HRH3
• HRH4
• HRH2
• CA1
• CA5A
• CA7
• Hrh1
• Hrh3
• Hrh4
• MIF
• NOX3

Mechanisms of action (all sources)

• Histamine receptor agonist
• HRH1 AGONIST
• Histamine H1 receptor agonist
• CA1 ACTIVATOR
• CA5A ACTIVATOR
• CA7 ACTIVATOR
• HRH1 FULL AGONIST
• HRH3 FULL AGONIST
• HRH4 FULL AGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• CA6
• CA5B
• CA4
• DRD1
• CA14
• CA13
• ACHE
• S1PR1
• PTGS1
• POLI
• PGR
• PDE4A
• PDE3A
• OPRM1
• OGG1
• NTHL1
• NEIL2
• NEIL1
• MUTYH
• MPG
• MBD4
• MAOA
• LMNA
• RGS4
• SLC22A2
• SAMHD1
• SLCO1B1
• UNG
• TSHR
• TDG
• TBXA2R
• SMUG1
• SMN1
• SLCO1B3
• SLC6A4
• SLC22A1
• SLC6A3
• SLC6A2
• SLC47A2
• SLC47A1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ARNT
• KSYK
• SYK
• TACC3
• UBP1

Drug classes

• Histamine Agents
• Neurotransmitter Agents
• Histamine Agonists

ATC classes

• L03A · IMMUNOSTIMULANTS
• V04C · OTHER DIAGNOSTIC AGENTS

Cross-references

• PubChem CID: 774
• ChEMBL: CHEMBL90
• DrugBank: DB05381
• ChEBI: CHEBI:18295
• KEGG: D04444
• RxNorm: 5333
• PDB: HSM
• Wikipedia: Histamine
• TTD: D04USC
• LINCS BRD: BRD-K01674964

Synonyms

• HISTAMINE PHOSPHATE
• ceplene
• 5-imidazoleethylamine
• eramin
• ergamine
• ergotidine
• histamine dihydrochloride
• histamine phosphate
• histamine diphosphate
• Ergamine
• Ergotidine
• NSC-33792
• Eramin
• Histaminum
• Istamina
• Theramine
• Free histamine
• Histamine Base
• Histamine [USAN]
• Istamina [Italian]
• H7125_SIGMA
• [3H]histamine
• ALBB-005968
• Beta-Aminoethylglyoxaline
• Beta-Aminoethylimidazole
• Beta-aminothethylglyoxaline
• Histamine (DCF)
• Histamine, Free Base
• Histaminum (TN)
• L-histamine
• ZERO/004089
• Imidazole-4-ethylamine
• Beta-Imidazolyl-4-ethylamine
• F411C768-A159-4FC0-A195-291A08BB03AA
• 1H-Imidazole-4-ethanamine
• 1H-Imidazole-5-ethanamine
• 2-(1H-Imidazol-4-yl)ethanamine
• 2-(1H-imidazol-5-yl)ethanamine