← SynDRA
AMPHOTERICIN B
SynDRA canonical compound SYN0000489 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | membrane permeability enhancer |
|---|
| Indication | fungal infection |
|---|
| Disease area | infectious disease |
|---|
Mechanisms of action (all sources)
- membrane permeability enhancer
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS2
- ACHE
- MAPK14
- NR1I2
- NR1H4
- NPY2R
- NPY1R
- NFE2L2
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK1
- OPRD1
- MAOB
- MAOA
- LMNA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH2
- NR3C1
- OPRK1
- ADORA1
- SLC29A1
- VDR
- TNF
- TDP1
- TBXAS1
- TBXA2R
- TACR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- CP3A7
- GCR
- NF2L2
- TRHR
Drug classes
- Polyene Antifungal
- Lipid-based Polyene Antifungal
- Anti-Infective Agents
- Antifungal Agents
- Antiparasitic Agents
- Antiprotozoal Agents
- Drug Carriers
- Liposomes
- Amebicides
- Anti-Bacterial Agents
ATC classes
- J02A · ANTIMYCOTICS FOR SYSTEMIC USE
- A01A · STOMATOLOGICAL PREPARATIONS
- A07A · INTESTINAL ANTIINFECTIVES
- G01A · ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Cross-references
Synonyms
- ABELCET
- AMBISOME
- AMPHOTEC
- Abelcet
- AmBisome
- FUNGIZONE
- abelcet
- abelecet
- amphocin
- amphozone
- apothecon
- fungilin
- Amphotericin B liposome
- Amphotericin
- Amphotericine b
- Amfotericina b
- Amphotericin b lipid complex
- Amphotericin b liposomal complex
- Abelcet, liposomal amphotericin b
- Ambil
- Amphotericin b deoxycholate
- Amphotericin b liposomal
- Amphotericin b liposome
- Amphotericin b, liposome
- Amphotericinum b
- Amphotocerin
- Halizon
- NSC-527017
- Ambisome
- Amophotericin b
- Ampho-moronal
- Amphotec
- Amphotercin b
- Amphotericitin b
- Amphotreicin b
- Ampotericin b
- Fungilin
Reported adverse events
- Back pain
- Chest pain
- Headache
- Hypotension
- Nausea
- Rash
- Abdominal pain
- Acidosis
- Agitation
- Alopecia
- Anxiety
- Arrhythmia
Look up AMPHOTERICIN B in the interactive SynDRA portal →