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ROQUINIMEX
SynDRA canonical compound SYN0000486 — structure-anchored drug synonym record
Clinical phase
Phase 3
Mechanism of action
angiogenesis inhibitor | tumor necrosis factor production inhibitor
All known targets
IL2
Mechanisms of action (all sources)
angiogenesis inhibitor
tumor necrosis factor production inhibitor
IL2 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
NR1I2
ADORA2A
ADORA3
SLC6A2
PGR
PDE4D
PDE3A
MC3R
MAOA
HTR2A
HRH1
HDAC6
DRD2
CYP3A4
CYP2D6
CYP2C9
CYP2C19
CYP1A2
CHRNA4
CHRM1
ADRB1
ADRA2C
ADRA1A
SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
KSYK
SYK
Drug classes
Adjuvants, Immunologic
Angiogenesis Inhibitors
Antineoplastic Agents
Growth Inhibitors
Growth Substances
Immunologic Factors
ATC classes
L03A · IMMUNOSTIMULANTS
Cross-references
PubChem CID:
54676478
ChEMBL:
CHEMBL11672
DrugBank:
DB11366
ChEBI:
CHEBI:92056
KEGG:
D05756
Wikipedia:
Linomide
TTD: D0G9ZW
LINCS BRD: BRD-K03384561
Synonyms
linomide
LS-2616
Linomide
FCF-89
LS 2616
4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
N-phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-quinoline-3-carboxamide
1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-3-quinolinecarboxanilide
NCGC00025172-01
372T2944C0
1,2-Dihydro-4-hydroxy-N,N-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide
3-Quinolinecarboxamide, 1,2-dihydro-4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl
Roquinimexum [Latin]
Roquinimexum
Roquinimex [USAN:INN]
CAS-84088-42-6
CCRIS 7673
PNU-212616
UNII-372T2944C0
Roquinimex(Linomide)
Tocris-1461
ROQUINIMEX [MI]
ROQUINIMEX [INN]
Roquinimex (USAN/INN)
ROQUINIMEX [USAN]
ROQUINIMEX [MART.]
FCF89
ROQUINIMEX [WHO-DD]
SCHEMBL42132
CHEMBL11672
SCHEMBL1651117
DTXSID4045680
CHEBI:92056
LS2616;FCF89
4-hydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide
HMS3267L20
HMS3412D07
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