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CHLORPROPAMIDE
SynDRA canonical compound SYN0000473 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | ABCC8 |
|---|
| Mechanism of action | ATP channel blocker |
|---|
| Indication | diabetes mellitus |
|---|
| Disease area | endocrinology |
|---|
All known targets
- ABCC8
- KCNJ11
- KCNJ10
- Slc22a6
Mechanisms of action (all sources)
- ATP channel blocker
- KCNJ11 BLOCKER
- Sulfonylurea receptor 1, Kir6.2 blocker
- ABCC8 BLOCKER
- ABCC8 INHIBITOR
- KCNJ10 BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- HTR2A
- ABCB1
- MC5R
- MAPK1
- MAPK14
- MAPK3
- MC3R
- MC4R
- MLNR
- LMNA
- MMP1
- MMP9
- NFKB1
- NPSR1
- NPY1R
- MAOA
- KCNH2
- LCK
- NR3C1
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GIPR
- GHSR
- NPY2R
- NTSR1
- FYN
- SLC10A1
- TSHR
- THRB
- TBXAS1
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Hypoglycemic Agents
- Sulfonylurea
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- DIABINESE
- GLUCAMIDE
- chlorodiabina
- chloronase
- chloropropamide
- chlorpropamid
- Clorpropamida
- NSC-44634
- NSC-626720
- Diabemide
- Diabinese
- Glucamide
- Glymese
- Melitase
- Adiaben
- Asucrol
- Bioglumin
- Catanil
- Chlorodiabina
- Chloronase
- Chloropropamide
- Chlorporpamide
- Chlorpropamid
- Chlorpropamidum
- Clorpropamid
- Clorpropamide
- Diabaril
- Diabechlor
- Diabenal
- Diabenese
- Diabeneza
- Diabetoral
- Diabexan
- Dynalase
- Glisema
- Insogen
- Insulase
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