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HEXACHLOROPHENE
SynDRA canonical compound SYN0000468 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ENPP2 | GLUD1 | SDHD |
|---|
| Mechanism of action | potassium channel activator |
|---|
| Indication | gram-positive bacterial infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
- NAPEPLD
- ACHE
- ADORA2A
- MAPK1
- MAPK14
- MAPK3
- MIF
- Malaria gdh
- Napepld
- PTGS2
- SDHD
- SLC6A4
Mechanisms of action (all sources)
- NAPEPLD INHIBITOR
- potassium channel activator
- Malaria gdh INHIBITOR
- fabI INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS1
- PGR
- PDE3A
- CASP1
- GALK1
- SLC6A2
- PDE4A
- NPY2R
- NPY1R
- HTR1A
- DRD3
- ADRB2
- ADRA1A
- DRD1
- OPRM1
- POLB
- PAX8
- PLK1
- POLH
- PDE5A
- POLI
- PPARD
- PPARG
- OPRD1
- OPRK1
- PRKCA
- NR3C1
- NR1H4
- NPC1
- NFKB1
- NFE2L2
- MMP9
- MMP1
- MCL1
- MC5R
- MC4R
- MC3R
- MAPT
- PPP3CA
- ADORA1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- PRKN
- PRGR
- PPP1CA
- PPME1
- PPM1D
- PHGDH
- PE2R2
- PAFA2
- PAFA
- PABP1
- PA21B
- NTMT1
- NTM1A
- NSD2
- NR1I2
- NOD1
- NLRP1
- NF2L2
- PRIO
- RARA
- ACES
- RPGF3
- UBP1
- UBA2
- TRHR
- TRFR
- THB
- TERA
- SYK
- STK33
- STAT1
- SIRT5
- SERPINE1
- SC6A3
- SC5A7
- SAE1
- S12A5
- RXFP1
- RPGF4
Drug classes
- Antiseptic
- Anti-Infective Agents
- Anti-Infective Agents, Local
ATC classes
- D08A · ANTISEPTICS AND DISINFECTANTS
Cross-references
Synonyms
- DIAL
- E-Z SCRUB
- E-Z Scrub
- GAMOPHEN
- GERMA-MEDICA
- GERMA-MEDICA "MG"
- HEXA-GERM
- HEXASCRUB
- PHISO-SCRUB
- PHISOHEX
- PRE-OP
- PRE-OP II
- almederm
- dermadex
- exofene
- hexachlorofen
- hexachlorophen
- hexophene
- Hexaclorofeno
- NSC-49115
- Dial
- E-z scrub
- Gamophen
- Germa-medica
- Germa-medica "mg"
- Hexa-germ
- Hexascrub
- Phiso-scrub
- Phisohex
- Pre-op
- Pre-op ii
- Scrubteam surgical spongebrush
- Septi-soft
- Septisol
- Soy-dome
- Turgex
- Acigena
- Almederm
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