← SynDRA

JDTIC

SynDRA canonical compound SYN0000464 — structure-anchored drug synonym record

All known targets

• OPRK1

Mechanisms of action (all sources)

• Opioid receptor antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• KCNH2
• OPRD1
• OPRM1
• HDAC6
• MRGPRX2

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2D6
• KSYK
• MAPK10
• MAPK8
• MAPK9
• NSD2
• SYK

Cross-references

• PubChem CID: 9956146
• ChEMBL: CHEMBL415247
• PDB: JDC
• Wikipedia: JDTic
• TTD: D0UG5M
• LINCS BRD: BRD-K95837862

Synonyms

• Rti-jdtic
• CHEMBL415247
• (3r)-7-Hydroxy-N-{(2s)-1-[(3r,4r)-4-(3-Hydroxyphenyl)-3,4-Dimethylpiperidin-1-Yl]-3-Methylbutan-2-Yl}-1,2,3,4-Tetrahydroisoquinoline-3-Carboxamide
• (3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
• (3R)-7-HYDROXY-N-((1S)-1-{[(3R,4R)-4-(3-HYDROXYPHENYL)-3,4-DIMETHYL-1-PIPERIDINYL]METHYL}-2-METHYLPROPYL)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXAMIDE
• JDC
• 3C6FZ6UXC8
• compound 10 [PMID: 11495579]
• compound 10 (PMID: 11495579)
• RefChem:150455
• DTXCID90384129
• CS-0537
• UNII-3C6FZ6UXC8
• GTPL7362
• orb3029210
• SCHEMBL3894627
• SCHEMBL29484941
• SCHEMBL30007617
• ZLVXBBHTMQJRSX-VMGNSXQWSA-N
• EX-A3812
• BDBM50130563
• AKOS027263824
• NCGC00378654-01
• HY-10486
• T11721
• BRD-K95837862-300-01-7
• atrans-(3R,4R)-dimethyl-4-(3-hydroxyphenyl) piperidine
• Jdtic hydrochloride
• GLXC-04046
• (3R)-1,2,3,4-Tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoquinolinecarboxamide hydrochloride
• JDTic 2HCl
• UNII-VR27M77CW3
• T11721L
• F84481
• JDTic dihydrochloride?
• DA-54521
• AKOS030526902