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HYDROXYCAMPTOTHECIN
SynDRA canonical compound SYN0000447 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | TOP1 |
|---|
| Mechanism of action | topoisomerase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- topoisomerase inhibitor
- TOP1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALB
- CASP1
- CASP7
- CYP3A4
- HBB
- HDAC6
- KAT2A
- SMN1
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ATXN2
- CP3A4
- HLAB
- IFNB1
- IFNG
- KSYK
- MITF
- NSD2
- PARP1
- SYK
- TFE3
- TP53
- YAP1
Drug classes
- Antineoplastic Agents, Phytogenic
Cross-references
Synonyms
- (s)-10-hydroxycamptothecin
- 10-hcpt
- 10-hydroxy-camptothecin
- 10-hydroxycamptothecin
- 10-hydroxycamptothecine
- NSC-107124
- Irinotecan related compound a
- (S)-10-Hydroxycamptothecin
- 10-Hydroxy-Camptothecin
- Hydroxycamptothecine
- Camptothecin, hydroxy-
- (S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- Camptothecin, 10-hydroxy-
- Camptothecine, 10-hydroxy-
- UNII-9Z01632KRV
- NSC 107124
- HCPT
- (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- (S)-10-Hydroxycamptothecin hydrate
- NSC107124
- BRD-K63784565
- 9Z01632KRV
- RefChem:77529
- MFCD02093100
- Hydroxy camptothecine
- CAMPTOTHECIN, 10-HYDROXY
- Hydroxycamptothecin-10
- Spectrum_001639
- (+)-(S)-10-HYDROXYCAMPTOTHECIN
- SpecPlus_000763
- Spectrum2_001660
- Spectrum3_001621
- Spectrum4_001815
- Spectrum5_000549
- ethyl(dihydroxy)[?]dione
- SCHEMBL25875
- BSPBio_003281
- KBioGR_002454
- KBioSS_002119
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