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SB-222200
SynDRA canonical compound SYN0000441 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | TACR3 |
|---|
| Mechanism of action | Tachykinin antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Tachykinin antagonist
- TACR3 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- FFAR4
- TACR2
- ADGRF1
- NTHL1
- KCNH2
- KMT2A
- MAPK1
- MPG
- MUTYH
- NEIL1
- NEIL2
- NFKB1
- NPSR1
- OGG1
- HDAC6
- PMP22
- S1PR1
- SMN1
- SMUG1
- TACR1
- TDG
- TDP1
- TP53
- TSHR
- UNG
- HIF1A
- GPR35
- ADRA2A
- C5AR1
- ADRB2
- AGTR1
- ALDH1A1
- ALOX15B
- APEX1
- APLNR
- ATAD5
- ATM
- ATXN2
- BLM
- CBX1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2C9
- CP2CJ
- CP3A4
- ESRRA
Cross-references
Synonyms
- SB222200
- S 5192
- N-(alpha-ethylbenzyl)-3-methyl-2-phenylquinoline-4-carboxamide
- (S)-3-Methyl-2-phenyl-N-(1-phenylpropyl)-4-quinolinecarboxamide
- 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
- SB 222200
- RefChem:931337
- MFCD00944072
- C26H24N2O
- SMR000326963
- Lopac-S-5192
- MQNYRKWJSMQECI-QFIPXVFZSA-N
- Tocris-1393
- Lopac0_000100
- MLS000862200
- MLS001056793
- GTPL2131
- orb1307756
- SCHEMBL3105312
- SCHEMBL29407508
- CHEBI:92079
- HMS2232O13
- HMS3260C22
- HMS3267F04
- HMS3412K20
- HMS3676K20
- EX-A7938
- Tox21_500100
- BDBM50051295
- AKOS024456569
- CCG-204195
- CS-1647
- EBC-519568
- LP00100
- SDCCGSBI-0050088.P002
- NCGC00015956-01
- NCGC00015956-02
- NCGC00015956-03
- NCGC00015956-04
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