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IDAZOXAN
SynDRA canonical compound SYN0000426 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | ADRA2A |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
All known targets
- ADRA2A
- ADRA2C
- ADRA2B
- NISCH
- PTGS2
- TADA2A
Mechanisms of action (all sources)
- Adrenergic receptor antagonist
- ADRA2A ANTAGONIST
- Adrenergic receptor alpha-2 antagonist
- ADRA2C ANTAGONIST
- ADRA2B ANTAGONIST
- TADA2A ANTAGONIST
- ADRA2C MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- MAOA
- MAOB
- ATXN2
- BAZ2B
- SMAD3
- SLC6A2
- SAMHD1
- RGS4
- RAB9A
- PTH1R
- PMP22
- OPRM1
- NPSR1
- NPC1
- NFE2L2
- MTOR
- MPHOSPH8
- MAPT
- ALDH1A1
- ATAD5
- LMNA
- KDM4E
- KCNH2
- HDAC6
- GMNN
- GLP1R
- EHMT2
- CBX1
- BLM
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADRA1B
- MDM4
- TSHR
- TP53
- SMAD2
- RARA
- PRGR
- PPARD
- NTM1A
- NSD2
- NR1I2
- NR1H4
- NF2L2
- MDM2
- ADRA1D
- IP6K1
- IL1B
- HTT
- HSPB1
- GLI3
- GEMI
- ESRRA
- ESR2
- CP2D6
- CP19A
- ANDR
- VDR
Drug classes
- Adrenergic alpha-2 Receptor Antagonists
Cross-references
Synonyms
- Idazoxano
- Dl-idazoxan
- Racemic idazoxan
- NSC-759867
- RX-781094
- Idazoxane
- Idazoxanum
- 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
- 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole
- CHEMBL10316
- CHEBI:5862
- Y310PA316B
- NSC 759867
- NCGC00015560-06
- Idazoxane [French]
- Idazoxanum [Latin]
- Idazoxano [Spanish]
- 4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole
- 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-
- CAS-79944-58-4
- Idazoxan [INN:BAN]
- idasoxan
- UNII-Y310PA316B
- IDAZOXAN [INN]
- IDAZOXAN [MI]
- Prestwick0_000926
- Prestwick1_000926
- Prestwick2_000926
- Prestwick3_000926
- (+-)-2-(1,4-Benzodioxan-2-yl)-2-imidazoline
- Lopac0_000652
- US8633208, Idazoxan
- (+/-)-IDAZOXAN
- BSPBio_000832
- SCHEMBL114731
- SPBio_003011
- BPBio1_000916
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