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PIRENZEPINE
SynDRA canonical compound SYN0000425 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CHRM1 |
|---|
| Mechanism of action | Acetylcholine receptor antagonist |
|---|
| Indication | peptic ulcer disease (PUD) |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- CHRM1
- CHRM2
- CHRM3
- CHRM4
- CHRM5
- ADORA3
- Chrm1
- Chrm2
- Chrm3
- Chrm4
- Chrm5
- GPM3
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- TAS2R9 AGONIST
- CHRM2 ANTAGONIST
- CHRM3 ANTAGONIST
- CHRM4 ANTAGONIST
- CHRM5 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- ACHE
- HTR2B
- KCNH2
- KDR
- LMNA
- MAOA
- OPRM1
- PDE3A
- PDE4A
- PGR
- POLH
- PTGS1
- RGS4
- SAMHD1
- SLC47A1
- SLC47A2
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TBXA2R
- KAT2A
- HTR1A
- ADRA1A
- HRH3
- ADRA2A
- ALDH1A1
- APEX1
- AR
- ATAD5
- CBX1
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- DRD3
- EHMT2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM2
- ACM3
- ACM4
- ACM5
- CP2D6
Drug classes
- Anti-Ulcer Agents
- Cholinergic Agents
- Cholinergic Antagonists
- Gastrointestinal Agents
- Muscarinic Antagonists
- Neurotransmitter Agents
ATC classes
- A02B · DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Cross-references
Synonyms
- pirenzepine hydrochloride hydrate
- pirenzepin
- pirenzepine dihydrochloride
- pirenzepine hydrochloride
- pirenzepine HCl
- Pirenzepina
- Wst-057
- 350320
- 9110700
- ACI-91
- Gastri p
- Gastrozepin
- Gasteril
- Gastrotsepin
- Pirenzepin
- Pirenzepinum
- Pyrenzepine
- Ulcosan
- Pirenzepine Gastrozepin
- Gastrozepin (TN)
- L-S 519
- Pirenzepina [INN-Spanish]
- Pirenzepine (INN)
- Pirenzepine [INN:BAN]
- Pirenzepinum [INN-Latin]
- 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one
- 11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
- 11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
- 5,11-Dihydro-11-((4-methyl-1-piperazinyl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one
- WST-057
- LS 519
- 3G0285N20N
- CHEBI:8247
- DTXCID303487
- Piren basan
- Pirenzepin ratiopharm
- Von Ct, Pirenzepin
- RefChem:174513
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