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CHLOROQUINE
SynDRA canonical compound SYN0000415 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP2C8 | MRGPRX1 |
|---|
| Mechanism of action | antimalarial agent |
|---|
| Indication | amebiasis | malaria |
|---|
| Disease area | infectious disease |
|---|
All known targets
- MRGPRX1
- ACKR1
- DHFR
- TAS2R3
- SIGMAR1
- S
- PRNP
- NR4A2
- NQO2
- MTOR
- KCNH2
- CYP2C8
Mechanisms of action (all sources)
- MRGPRX1 AGONIST
- TAS2R3 AGONIST
- ACKR1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACE2
- NSD1
- CXCR4
- ABCB1
- NPY1R
- OPRM1
- OPRK1
- OPRD1
- NR4A3
- NR4A1
- NR3C1
- NR1I2
- MLNR
- MC4R
- MC3R
- MAPT
- MAOA
- KDM4E
- HTR3A
- HTR2C
- HTR2B
- PDE3A
- PDE4D
- HTR1A
- PGR
- TLR9
- TLR7
- TDP1
- TBXA2R
- SLCO2B1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC47A2
- SLC47A1
- SLC2A1
- SLC29A1
- SLC22A1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACES
- ACM1
- ANDR
- COMT
- CP2D6
- GAMT
- GLI3
- GNMT
- HNMT
- KSYK
- MDR1
- NNMT
- PNMT
- PRGR
- SYK
Drug classes
- Antimalarial
- Analgesics
- Analgesics, Non-Narcotic
- Anthelmintics
- Anti-Infective Agents
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antimalarials
- Antinematodal Agents
- Antiparasitic Agents
- Antiprotozoal Agents
- Antirheumatic Agents
ATC classes
Cross-references
Synonyms
- ARALEN
- ARALEN HYDROCHLORIDE
- ARALEN PHOSPHATE W/ PRIMAQUINE PHOSPHATE
- CHLOROQUINE PHOSPHATE
- chloroquine sulfate
- chloroquine phosphate
- chloraquine
- chlorochin
- chloroquine hydrochloride
- chloroquine diphosphate
- chloroquine HCl
- chloroquine sulphate
- Cloroquina
- NSC-187208
- Amokin
- Aralen
- Aralen HCl
- Arechin
- Arechine
- Arequin
- Arolen
- Arthrochin
- Artrichin
- Avlochlor
- Avloclor
- Bemaco
- Bemaphate
- Bemasulph
- Benaquin
- Bipiquin
- CU-01000012392-2
- Capquin
- Chemochin
- Chingamin
- Chloraquine
- Chlorochin
- Chlorochine
- Chlorochinum
Reported adverse events
- Erythema multiforme
- Hepatitis
- Hypotension
- Maculopathy
- Pancytopenia
- Stevens-Johnson syndrome
- Urticaria
- Sensorimotor disorder
- Erythema
- Cardiac disorder
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