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TENOFOVIR ANHYDROUS
SynDRA canonical compound SYN0000385 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | FOLH1 |
|---|
| Mechanism of action | glutamate receptor antagonist |
|---|
All known targets
- HBcAg
- HIV RT
- pol
- reverse transcriptas
- GAG-POL
- CYP1A2
- CYP3A4
- HIV IN
- gag-pol
Mechanisms of action (all sources)
- HIV integrase INHIBITOR
- nucleoside reverse transcriptase inhibitor
- HIV RT INHIBITOR
- hiv gag INHIBITOR
- HIV RT MODULATOR
- HIV IN INHIBITOR
- pol INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCC1
- MAOA
- NR1I2
- NPY1R
- MLNR
- MC4R
- MC3R
- MAPDA
- KCNH2
- OPRD1
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- NR3C1
- OPRK1
- ABCC2
- SLC29A1
- SLCO2B1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC22A8
- OPRM1
- SLC22A6
- PTGS2
- POLG
- PGR
- PDE4D
- PDE3A
- HRH2
- HRH1
- HDAC6
- ADRA2B
- AK2
- AK1
Drug classes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Enzyme Inhibitors
- Nucleic Acid Synthesis Inhibitors
- Reverse Transcriptase Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- Atripla
- Truvada
- Viread
- tenofovir
- tenofovir hydrate
- tenefovir
- GS-1275
- Tenofovir
- Apropovir
- PMPA
- TFV
- Tenefovir
- GS 1275
- GS 1278
- GS1278
- GNA & Tenofovir
- HHA & Tenofovir
- KS-5021
- Viread (TN)
- Viread, Tenofovir
- D,L-Tenofovir
- PMPA-(R)
- Phosphonic acid, [[2-(6-amino-9H-purin-9
- (R)-9-(2-Phosphonomethoxypropyl)adenine
- (R)-9-(2-Phosphonylmethoxypropyl)adenine
- (R)-PMPA
- Tenofovir hydrate
- TENOFOVIR
- tenofovir monohydrate
- PMP-A
- GS-1278
- 9-((R)-2-PHOSPHONOMETHOXY-PROPYL)ADENINE MONOHYDRATE
- W4HFE001U5
- tenofovir (usp-rs)
- tenofovir (anhydrous)
- anhydrous tenofovir
- tenofovir (anh.)
- CHEBI:63625
- (R)-9-(Phosphonomethoxypropyl)adenine
Reported adverse events
- Lactic acidosis
- Lactic acid
- Fanconi syndrome
- Rash
- Dizziness
- Headache
- Hepatomegaly
- Nausea
- Insomnia
- Arthralgia
- Vomiting
- Depression
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