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LANSOPRAZOLE
SynDRA canonical compound SYN0000381 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ATP4A |
|---|
| Mechanism of action | ATPase inhibitor |
|---|
| Indication | heartburn |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- ATP4A
- ATP4B
- CYP2C19
- ABCG2
- CYP2D6
- CYP3A4
- CYP3A5
- DDAH1
- ENGASE
- FASN
- Ido1
- Ido2
Mechanisms of action (all sources)
- ATPase inhibitor
- ATP4A INHIBITOR
- Potassium-transporting ATPase inhibitor
- ATP4B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- OPRK1
- GHSR
- SARM1
- PPIA
- CYP2C8
- HTR3A
- TBXA2R
- CYP1A2
- OPRM1
- ADORA3
- OPRD1
- HRH2
- DRD4
- NFE2L2
- MPHOSPH8
- MAPK3
- MMP9
- NPC1
- MMP1
- MLNR
- MDH1
- MC5R
- MC4R
- MC3R
- MAOA
- MAPK14
- HTR7
- HSD17B10
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR6
- IDE
- MAPK1
- KCNH2
- KDM4A
- KDM4E
- LCK
- LMNA
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- KSYK
- SYK
- RARA
- PRMT1
- PPARG
- PNMT
- PHOP1
- NTMT1
- NTM1A
- NR1I2
- NNMT
- NF2L2
- MCL1
- LOX15
- LOX12
- KMT2A
- ALOX12
- HNMT
- GPX4
- GPR32
- GNMT
- GAMT
- ESRRA
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- COMT
- ALR
- WDR5
Drug classes
- Proton Pump Inhibitors
- Proton Pump Inhibitor
- Anti-Ulcer Agents
- Enzyme Inhibitors
- Gastrointestinal Agents
ATC classes
- A02B · DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Cross-references
Synonyms
- LANSOPRAZOLE, AMOXICILLIN AND CLARITHROMYCIN (COPACKAGED)
- PREVACID
- PREVACID 24 HR
- PREVACID IV
- PREVACID NAPRAPAC 250 (COPACKAGED)
- PREVACID NAPRAPAC 375 (COPACKAGED)
- PREVACID NAPRAPAC 500 (COPACKAGED)
- PREVPAC (COPACKAGED)
- Prevacid
- prevacid
- A-65006
- AG-1749
- Lansoprazol
- Agopton
- Lansox
- Lanzoprazole
- Lanzor
- Limpidex
- Ogast
- Ogastoro
- Prevonco
- Takepron
- NSC-758638
- Lansoprazole component of prevpac
- Opiren
- Prevacid 24 hr
- Prevacid delayed release
- Prevacid iv
- Prevacid solutab
- Zoton
- A 65006
- PREVPAC COMPONENT LANSOPRAZOLE
- lanzoprazole
- AG 1749
- lansoprazole (ep monograph)
- lansoprazole (usp monograph)
- PrevOnco
Reported adverse events
- Headache
- Nausea
- Constipation
- Fracture
- Stevens-Johnson syndrome
- Hypersensitivity
- Agranulocytosis
- Arthralgia
- Malaise
- Myalgia
- Rash
- Stomatitis
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