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HEXESTROL
SynDRA canonical compound SYN0000365 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ESR1 |
|---|
| Mechanism of action | Estrogen receptor agonist |
|---|
| Indication | hypoestrogenism |
|---|
| Disease area | endocrinology |
|---|
All known targets
Mechanisms of action (all sources)
- ESR1 AGONIST
- ESR1 INHIBITOR
- ESR2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLC6A2
- AR
- PGR
- SLC6A3
- ADORA3
- SNCA
- SMAD3
- KDR
- LMNA
- MAOA
- MAPT
- OPRM1
- PDE3A
- PDE4A
- TDP1
- PTGS1
- PTH1R
- SAMHD1
- KCNH2
- TBXA2R
- SLC6A4
- SLCO1B1
- SLCO1B3
- TARDBP
- ACHE
- HTR2B
- IDH1
- CYP2C9
- ADRA1A
- ADRA2A
- ALOX15
- ALOX15B
- APEX1
- CHRM1
- CHRM2
- CYP1A2
- CYP2C19
- CYP2D6
- HTR1A
- CYP3A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACM1
- SMAD2
- RARA
- PRGR
- PPARG
- NTMT1
- NTM1A
- NSD2
- NR1I2
- NF2L2
- HSPB1
- GLI3
- GEMI
- GCR
- ESRRA
- CP3A7
- CP3A4
- CP2CJ
- CP2C9
- CP1A2
- CP19A
- ANDR
- TP53
Drug classes
- Antineoplastic Agents
- Antineoplastic Agents, Hormonal
- Estrogens
- Estrogens, Non-Steroidal
- Hormones
- synthetic estrogen
Cross-references
Synonyms
- dihydrodiethylstilbestrol
- cycloestrol
- erythrohexestrol
- hexanoestrol
- hexestrofen
- hexoestrol
- hormoestrol
- mesohexestrol
- Erythrohexestrol
- Meso-hexestrol
- Mesohexestrol
- NSC-9894
- Dihydrodiethylstilbestrol
- Vitestrol
- Hexoestrolum
- Exestrol
- Stilbestrol, dihydro-
- 4,4'-(1,2-Diethylethylene)diphenol
- 4,4'-(hexane-3,4-diyl)diphenol
- Synoestrolum
- Hexanestrol
- Cycloestrol
- Esestrolo [DCIT]
- Phenol, 4,4'-(1,2-diethyl-1,2-ethanediyl)bis-
- Hexestrolum [INN-Latin]
- Hexane, 3,4-bis(4-hydroxyphenyl)-
- EINECS 227-082-2
- 3,4-Bis(p-hydroxyphenyl)hexane
- Hormoestrol
- Syntrogene
- Synthovo
- Phenol, 4,4'-(1,2-diethylethylene)di-
- CHEBI:31669
- PBBGSZCBWVPOOL-UHFFFAOYSA-N
- Hexestrol [INN]
- meso hexestrol
- Hexoestrol
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