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COMBRETASTATIN A4
SynDRA canonical compound SYN0000351 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Mechanism of action | tubulin polymerization inhibitor |
|---|
All known targets
- TUBB4B
- TUBB1
- TUBA3C
- TUBA4A
- TUBB3
- TUBA1A
- TUBB4A
- TUBB8
- TUBB
- TUBA1B
- TUBA1C
- TUBA3E
Mechanisms of action (all sources)
- tubulin polymerization inhibitor
- TUBB4B INHIBITOR
- TUBB1 INHIBITOR
- TUBA3C INHIBITOR
- TUBA4A INHIBITOR
- TUBB3 INHIBITOR
- TUBA1A INHIBITOR
- TUBB4A INHIBITOR
- TUBB8 INHIBITOR
- TUBB INHIBITOR
- TUBA1B INHIBITOR
- TUBA1C INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB1
- SLC22A2
- TUBB1
- SRC
- SLCO2B1
- SLCO1B3
- SLC22A8
- SLC22A6
- SLC22A1
- ABL1
- PDGFRB
- NPR1
- KDR
- HDAC6
- FGFR1
- EGFR
- TUBB3
Drug classes
- Antineoplastic Agents, Phytogenic
Cross-references
Synonyms
- Combretastatin a-4
- 2'-deoxycombretastatin a1
- Combrestatin a4
- Combretastatin 4
- CA4
- NSC-613729
- NSC-817373
- combretastatin-A-4
- Combrestatin A4
- 2'-deoxycombretastatin A1
- 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
- NSC 613729
- 3,4,5-Trimethoxy-3'-hydroxy-4'-methoxystilbene
- NSC613729
- 2-methoxy-5-((Z)-2-(3,4,5-trimethoxyphenyl)ethenyl)phenol
- RefChem:918948
- DTXCID80852504
- NSC817373
- NSC609397
- (Z)-2-METHOXY-5-(3,4,5-TRIMETHOXYSTYRYL)PHENOL
- MFCD03453309
- CA 4
- Crc 87-09
- NSC 817373
- 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]phenol
- 2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol
- UNII-16U6OP69RQ
- combretastin A4
- Crc-98-09
- Combrestatin A-4
- Combretastin A-4
- 2-methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
- Combretastastin A-4
- NSC 609397
- 2-methoxy-5-(3,4,5-trimethoxystyryl)phenol
- Z-Combretastatin A-4
- 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
- 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol
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