← SynDRA
NARINGENIN
SynDRA canonical compound SYN0000336 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | ESR2 |
|---|
| Mechanism of action | Aromatase inhibitor |
|---|
All known targets
- CYP19A1
- ESR2
- CYP1B1
- GLO1
- HSD17B1
- TAS2R39
- TRPM3
Mechanisms of action (all sources)
- TRPV antagonist
- CYP19A1 INHIBITOR
- TAS2R39 AGONIST
- TRPM3 MODULATOR
- GLO1 INHIBITOR
- ESR2 INHIBITOR
- CYP1B1 INHIBITOR
- HSD17B1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CA4
- OPRD1
- ABCC1
- OPRK1
- OPRM1
- SHBG
- CBR1
- TTR
- DPP4
- CA12
- CA7
- ABCB1
- PTH1R
- PTGS2
- PPARG
- PSMB5
- RAPGEF3
- PPARD
- PPARA
- PON1
- PDE5A
- PTPN1
- SLCO1B1
- SAMHD1
- NFE2L2
- SLCO1B3
- SLCO2B1
- SULT1E1
- TDP1
- TYR
- UGT1A1
- UGT1A10
- UGT1A3
- UGT1A4
- UGT1A8
- UGT2B15
- USP1
- NR3C1
- HSD17B2
- IPMK
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALR
- CP1A2
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
Drug classes
- Anti-Ulcer Agents
- Estrogen Antagonists
Cross-references
Synonyms
- 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
- 4',5,7-Trihydroxyflavanone
- Naringenine
- (+/-)-Naringenin
- naringetol
- salipurpol
- (-)-Naringenin
- NARIGENIN
- Salipurol
- 5,7,4'-Trihydroxyflavanone
- (S)-Naringenin
- BE-14348A
- NSC-34875
- ( inverted exclamation markA)-Naringenin
- CHEMBL32571
- MLS000738094
- MLS000028739
- CHEBI:50202
- Flavanone, 4',5,7-trihydroxy-
- FTVWIRXFELQLPI-UHFFFAOYSA-N
- NSC34875
- NSC11855
- MFCD00006844
- SMR000059039
- AK122638
- NSC-11855
- 4',7-Trihydroxyflavanone
- YSO1
- (-)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
- (-)-(2S)-Naringenin
- (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
- (2S)-4',5,7-trihydroxyflavan-4-one
- (2S)-4',5,7-trihydroxyflavanone
- (2S)-5,7,4'-trihydroxyflavone
- (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
- (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
- (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
- (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
Look up NARINGENIN in the interactive SynDRA portal →