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PODOFILOX
SynDRA canonical compound SYN0000318 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | IGF1R | TOP2A | TUBA4A | TUBB |
|---|
| Mechanism of action | microtubule inhibitor | tubulin polymerization inhibitor |
|---|
| Indication | genital warts |
|---|
| Disease area | infectious disease |
|---|
All known targets
- TOP2A
- TUBB
- TUBA4A
- CYP2C19
- TUBA3E
- TUBB6
- TUBB4B
- TUBB4A
- TUBB3
- TUBB2B
- TUBB2A
- TUBB1
Mechanisms of action (all sources)
- microtubule inhibitor
- tubulin polymerization inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- ESR1
- ACHE
- MAPK14
- OPRD1
- NR0B1
- NPY2R
- NPY1R
- NPC1
- NFE2L2
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAOA
- MAPK1
- OPRM1
- LMNA
- LCK
- KDR
- KCNH2
- IDH1
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- OPRK1
- PAX8
- HRH1
- PDE3A
- USP1
- TOP1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- A4
- PARP1
- MDM4
- MDR1
- MITF
- NF2L2
- NFKB1
- NR1H4
- NR1I2
- NSD2
- RARA
- ACM4
- RORA
- SMAD2
- SMAD3
- STK33
- SYK
- TF65
- TLR3
- VDR
- MDM2
- KSYK
- KLF5
- JUN
- AHR
- ANDR
- BARD1
- BRCA1
- CFTR
- CP1A2
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- CSTA
- ESRRA
- GEMI
- GLI3
- HTR1E
- IFNG
Drug classes
- Antimitotic Agents
- Antineoplastic Agents
- Antineoplastic Agents, Phytogenic
- Dermatologic Agents
- Keratolytic Agents
- Tubulin Modulators
ATC classes
- D06B · CHEMOTHERAPEUTICS FOR TOPICAL USE
Cross-references
Synonyms
- CONDYLOX
- Condylox
- podophyllotoxin
- condyline
- Podophyllotoxin
- NSC-24818
- Condyline
- Warticon
- Wartec
- Podophyllotoxin 7
- Podophyllinic acid lactone
- (-)-Podophyllotoxin
- Podofilox [USAN]
- CCRIS 565
- UNII-L36H50F353
- Podophyllotoxin, 95%
- HSDB 7238
- NSC24818
- CHEMBL61
- EINECS 208-250-4
- NSC 24818
- MLS000069495
- AI3-50456
- CHEBI:50305
- Podofilox (USAN)
- L36H50F353
- BRD-K47869605
- Podophyllum
- MFCD00075290
- NCGC00022001-05
- Podofilm
- SMR000059121
- Podocon-25
- Podophilox
- SR-05000001749
- MLS002702981
- Podofillina
Reported adverse events
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